RegulonDB RegulonDB 10.8: Operon Form
   

yegH operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yegH
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: yegH
Gene(s): yegH   Genome Browser M3D Gene expression COLOMBOS
Evidence: [AISDTU] Automated inference that a single-gene directon is a transcription unit
Promoter
Name: yegHp
+1: 2137863
Distance from start of the gene: 39
Sequence: atatgagataaatagtgctgcaacattgcatttttgccccgatttatccatgatcgaattGtgacatttgtcatacaacga
Evidence: [HTIM]
Reference(s): [1] Mendoza-Vargas A., et al., 2009
TF binding sites (TFBSs)
[PhoB,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd PhoB-Phosphorylated1 activator yegHp nd nd nd nd nd [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA] [2]
Note(s): 1Yang et al. identified the binding site of PhoB Yang C,2012but did not identify the promoter regulated; therefore, there is a possibility that this binding site corresponds to another promoter, according to the function of PhoB. The binding site of this regulator, TTGTATGACAAATGTCACA, is located at bp -31 relative to the translation start site of yegH Yang C,20121Yang et al. identified the binding site of PhoB Yang C,2012but did not identify the promoter regulated; therefore, there is a possibility that this binding site corresponds to another promoter, according to the function of PhoB. The binding site of this regulator, TTGTATGACAAATGTCACA, is located at bp -31 relative to the translation start site of yegH Yang C,2012


Evidence    

 [HTIM] High-throughput transcription initiation mapping

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [BPP] Binding of purified proteins

 [CV(CHIP-SV/GEA/ROMA)] cross validation(CHIP-SV/GEA/ROMA)

 [CV(GEA/ROMA)] cross validation(GEA/ROMA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Mendoza-Vargas A., Olvera L., Olvera M., Grande R., Vega-Alvarado L., Taboada B., Jimenez-Jacinto V., Salgado H., Juarez K., Contreras-Moreira B., Huerta AM., Collado-Vides J., Morett E., 2009, Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli., PLoS One 4(10):e7526

 [2] Yang C., Huang TW., Wen SY., Chang CY., Tsai SF., Wu WF., Chang CH., 2012, Genome-wide PhoB binding and gene expression profiles reveal the hierarchical gene regulatory network of phosphate starvation in Escherichia coli., PLoS One 7(10):e47314

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