RegulonDB RegulonDB 11.2: Operon Form
   

yrdA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yrdA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: yrdA
Gene(s): yrdA   Genome Browser M3D Gene expression COLOMBOS
Note(s): The deletion of the Fis DNA binding sites located upstream of the yrdAp promoter enhances the inhibition of yrdAp via transcription-coupled DNA supercoiling (TCDS) in the early log phase. Fis appears to block supercoiling diffusion close to yrdAp Dages S, Zhi X, Leng F,2020.
Evidence: [COMP-AINF-SINGLE-DIRECTON] Automated inference that a single-gene directon is a transcription unit
Promoter
Name: yrdAp
+1: Unknown
Sigma Factor: Sigma32 Sigmulon
Evidence: [EXP-IDA]
[EXP-IEP]
Reference(s): [1] Wade JT., et al., 2006


Evidence    

 [EXP-IDA] Inferred from direct assay

 [EXP-IEP] Inferred from expression pattern


Reference(s)    

 [1] Wade JT., Roa DC., Grainger DC., Hurd D., Busby SJ., Struhl K., Nudler E., 2006, Extensive functional overlap between sigma factors in Escherichia coli., Nat Struct Mol Biol 13(9):806-14

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