RegulonDB RegulonDB 11.1: Operon Form
   

blr operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: blr
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: blr
Gene(s): blr   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
[EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Wong RS., et al., 2000
Promoter
Name: blrp
+1: 1704512
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 39
Sequence: atcgcaaaaacctcagtaaaaatcttgctggagctattattgctaagtaacatttaccccCtgaagttaatggatcaatca
Evidence: [EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
[EXP-IEP]
[EXP-IPI]
[RS-EPT-CBR]
Reference(s): [2] Salgado H, et al., 2012
[3] Seo SW., et al., 2015
[1] Wong RS., et al., 2000


Evidence    

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping

 [EXP-IEP] Inferred from expression pattern

 [EXP-IPI] Inferred from physical interaction

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Wong RS., McMurry LM., Levy SB., 2000, 'Intergenic' blr gene in Escherichia coli encodes a 41-residue membrane protein affecting intrinsic susceptibility to certain inhibitors of peptidoglycan synthesis., Mol Microbiol 37(2):364-70

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Seo SW., Kim D., O'Brien EJ., Szubin R., Palsson BO., 2015, Decoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli., Nat Commun 6:7970

RegulonDB