RegulonDB RegulonDB 10.10: Operon Form
   

nepI operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: nepI
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: nepI
Gene(s): nepI   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
[ICWHO] Inferred computationally without human oversight
Reference(s): [1] Gronskiy SV., et al., 2005
Promoter
Name: nepIp
+1: 3841771
Distance from start of the gene: 32
Sequence: acaccgtaaaagttgcaaaaacgttaaatgcgtcacacatttcaatgttaaagtggtcggCttttcccctgaaacatgcca
Evidence: [HIPP]
[TIM]
Reference(s): [1] Gronskiy SV., et al., 2005
TF binding sites (TFBSs)
[SoxS,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal SoxS activator nepIp 3841756 3841775 6.0 gttaaagtggTCGGCTTTTCCCCTGAAACAtgccacgggt nd [RSE], [CEEUMA], [IHBCE] [2]


Evidence    

 [HIPP] Human inference of promoter position

 [TIM] Transcription initiation mapping

 [RSE] RNA-seq evidence

 [CEEUMA] ChIP-exo evidence used in manual assertion

 [IHBCE] Inferred by a human based on computational evidence


Reference(s)    

 [1] Gronskiy SV., Zakataeva NP., Vitushkina MV., Ptitsyn LR., Altman IB., Novikova AE., Livshits VA., 2005, The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides., FEMS Microbiol Lett 250(1):39-47

 [2] Seo SW., Kim D., Szubin R., Palsson BO., 2015, Genome-wide Reconstruction of OxyR and SoxRS Transcriptional Regulatory Networks under Oxidative Stress in Escherichia coli K-12 MG1655., Cell Rep 12(8):1289-99

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