RegulonDB RegulonDB 10.10: Operon Form
   

ravA-viaA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ravA-viaA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: ravA-viaA
Gene(s): viaA, ravA   Genome Browser M3D Gene expression COLOMBOS
Note(s): The ravA-viaA operon is induced in stationary phase by σS under aerobic growth conditions Snider J,2006.
σS differentially modulates the expression of the ravA and via genes under oxygen-limiting conditions Wong KS,2017.
A 7-nt consensus sequence for the NarL transcription factor (TACTCCT), centered 95 nt upstream of the ravA-viaA operon, was identified. However, mutation of this site had an effect on β-galactosidase activity Wong KS,2017.
Evidence: [ICWHO] Inferred computationally without human oversight
[ITCR] Inferred through co-regulation
Reference(s): [1] Snider J., et al., 2006
[2] Wong KS., et al., 2017
Promoter
Name: ravAp
+1: 3931128
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 35
Sequence: aaataccccccctttgagactattttagccaccagcaagaaacgtctatactcgcaatttAcgcagaacttttgacgaaag
                                              -10           +1                   
Evidence: [HTTIM]    
[IHBCE]
Reference(s): [3] Mendoza-Vargas A., et al., 2009
[4] Typas A., et al., 2007
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FNR activator ravAp 3931193 3931206 -71.5 tgcggccacaTTAACCTGGCTCAAagaaaaatac nd [GEA], [APIORCISFBSCS], [BPP], [SM] [2]
remote FNR activator ravAp 3931323 3931336 -201.5 cgggcaatgaTTGCTTATTATCAGtgctcataga nd [GEA], [APIORCISFBSCS], [BPP], [SM] [2]





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