RegulonDB RegulonDB 11.1: Operon Form
   

pitB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: pitB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: pitB
Gene(s): pitB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
[EXP-IMP] Inferred from mutant phenotype
Reference(s): [1] Hoffer SM., et al., 2001
Promoter
Name: pitBp
+1: 3136403
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 32
Sequence: tatcgttaaaaaatgatatttcactttgcccatgccgttaaagtcactgataatgcgtccGttcgtaaattcaaaatggcg
                               -35                    -10   +1                   
Evidence: [COMP-AINF]
[COMP-HINF-POSITIONAL-IDENTIFICATION]
Reference(s): [1] Hoffer SM., et al., 2001
[2] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[PhoB,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd PhoB-phosphorylated repressor pitBp nd nd nd nd nd [EXP-IMP] W [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-HINF-POSITIONAL-IDENTIFICATION] Human inference of promoter position

 [EXP-IMP] Inferred from mutant phenotype


Reference(s)    

 [1] Hoffer SM., Schoondermark P., van Veen HW., Tommassen J., 2001, Activation by gene amplification of pitB, encoding a third phosphate transporter of Escherichia coli K-12., J Bacteriol 183(15):4659-63

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Harris RM., Webb DC., Howitt SM., Cox GB., 2001, Characterization of PitA and PitB from Escherichia coli., J Bacteriol 183(17):5008-14

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