RegulonDB RegulonDB 10.9: Operon Form
   

csrA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: csrA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: csrA
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: csrAp5
+1: 2819189
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 43
Sequence: ttagatgtaatgtgtttgtcattgcttactttttggcgttatatgatggataatgccgggAtacagagagacccgactctt
                      -35                        -10        +1                   
Note(s): The csrAp5 is promoter is expressed during the transition from exponential to stationary phases Yakhnin H,2011
Evidence: [HIPP]
[ICWHO]
[RS-EPT-CBR]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[2] Salgado H, et al., 2012
[3] Yakhnin H., et al., 2011


Transcription unit       
Name: csrA
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: csrAp4
+1: 2819198
Distance from start of the gene: 52
Sequence:
Note(s): The csrAp4 promoter was identified by in vivo but not by in vitro experiments Yakhnin H,2011
Evidence: [HIPP]
[RS-EPT-CBR]
[TIM]
Reference(s): [2] Salgado H, et al., 2012
[3] Yakhnin H., et al., 2011


Transcription unit       
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: csrAp3
+1: 2819273
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 127
Sequence: aacgctatcgacaacgataaagtcaggttgaagttgtgtatatcggctaaacttaggtttAacagaatgtaatgccatgac
                        -35                -10              +1                   
Note(s): The csrAp3 promoter is highly expressed during the transition from exponential to stationary phase. This promoter is a strong σS-dependent promoter that is also activated by σ70. The protein CsrA appears to indirectly induce transcription of the csrA gene from the csrAp3 promoter Yakhnin H,2011
Evidence: [HIPP]
[HTTIM]    
[ICWHO]
[RS-EPT-CBR]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[4] Mendoza-Vargas A., et al., 2009
[2] Salgado H, et al., 2012
[3] Yakhnin H., et al., 2011


Transcription unit       
Name: csrA
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Promoter
Name: csrAp2
+1: 2819370
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 224
Sequence: ctgcagcgttagccagtgtgaaaggctgggtcagcgcgaaattgcaataatataagcgtcAggcaatgccgtggactcgct
                          -35                   -10         +1                   
Note(s): The csrAp2 promoter, which overlaps with the csrAp1 promoter, is a weak promoter whose activity is dependent on σ70 Yakhnin H,2011
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[3] Yakhnin H., et al., 2011


Transcription unit       
Name: csrA
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: csrAp
+1: 2819373
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 227
Sequence: tacctgcagcgttagccagtgtgaaaggctgggtcagcgcgaaattgcaataatataagcGtcaggcaatgccgtggactc
                         -35                -10             +1                   
Note(s): The csrAp1 promoter, which overlaps with the csrAp2 promoter, is a weak promoter that is activated by both σ70 and σS Yakhnin H,2011
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[3] Yakhnin H., et al., 2011


Transcription unit       
Name: csrA
Gene(s): csrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: csrAp1
+1: 2819373
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 227
Sequence: tacctgcagcgttagccagtgtgaaaggctgggtcagcgcgaaattgcaataatataagcGtcaggcaatgccgtggactc
                             -35                   -10      +1                   
Note(s): The csrAp1 promoter, which overlaps with the csrAp2 promoter, is a weak promoter that is activated by both σ70 and σS Yakhnin H,2011
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[3] Yakhnin H., et al., 2011





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