RegulonDB RegulonDB 10.10: Operon Form
   

sbmC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: sbmC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: sbmC
Gene(s): sbmC   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: sbmCp2
+1: 2081303
Distance from start of the gene: 41
Sequence: actggcaggagtgcgagtctgctcgcataatcaacactcattccttgtggttttaattttGcaactatactgtatataaaa
Note(s): sbmCp2 belongs to the group of promoters under control of CRP and Sxy, called CRP-S (Sxy-dependent CRP sites) Cameron AD,2006
Evidence: [HTTIM]
Reference(s): [1] Mendoza-Vargas A., et al., 2009
TF binding sites (TFBSs)
[CRP,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cyclic-AMP activator sbmCp2 2081334 2081355 -41.5 agactggcagGAGTGCGAGTCTGCTCGCATAAtcaacactca nd [AIBSCS], [BPP], [IHBCE] [2], [3]
[LexA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor sbmCp2 2081277 2081296 17.5 tttgcaactaTACTGTATATAAAAACAGTAtcaatggagg nd [GEA], [IHBCE] [2]


Transcription unit       
Name: sbmC
Gene(s): sbmC   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: sbmCp1
+1: 2081325
Distance from start of the gene: 63
Sequence: cctgacctttcttttgcagcagactggcaggagtgcgagtctgctcgcataatcaacactCattccttgtggttttaattt
Evidence: [HTTIM]
Reference(s): [1] Mendoza-Vargas A., et al., 2009


Evidence    

 [HTTIM] High-throughput transcription initiation mapping

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [IHBCE] Inferred by a human based on computational evidence

 [GEA] Gene expression analysis


Reference(s)    

 [1] Mendoza-Vargas A., Olvera L., Olvera M., Grande R., Vega-Alvarado L., Taboada B., Jimenez-Jacinto V., Salgado H., Juarez K., Contreras-Moreira B., Huerta AM., Collado-Vides J., Morett E., 2009, Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli., PLoS One 4(10):e7526

 [2] Baquero MR., Bouzon M., Varea J., Moreno F., 1995, sbmC, a stationary-phase induced SOS Escherichia coli gene, whose product protects cells from the DNA replication inhibitor microcin B17., Mol Microbiol 18(2):301-11

 [3] Jackson RJ., Binet MR., Lee LJ., Ma R., Graham AI., McLeod CW., Poole RK., 2008, Expression of the PitA phosphate/metal transporter of Escherichia coli is responsive to zinc and inorganic phosphate levels., FEMS Microbiol Lett 289(2):219-24

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