RegulonDB RegulonDB 10.10: Operon Form

rplY operon and associated TUs in Escherichia coli K-12 genome

Name: rplY
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit       
Gene(s): rplY   Genome Browser M3D Gene expression COLOMBOS
Note(s): The G/C-rich discriminator sequence is located just downstream from the -10 box in the rplY promoter, suggesting possible negative regulation by ppGpp during the stringent response Aseev LV,2015
Evidence: [ICWHO] Inferred computationally without human oversight
Reference(s): [1] Uemura Y., et al., 1991
Name: rplVp
+1: 2282440
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 77
Sequence: attacgcggttaatggtagttttgattgatgtataaggcgattgagtatagaatctcgccCgcttttgcatacgcaaagca
                          -35                    -10        +1                   
Evidence: [AIPP]
Reference(s): [2] Aseev LV., et al., 2015
Type: rho-independent
Sequence: ttgtaaaaaaCCCCGCTCCGGCGgggttttttg
Reference(s): [2] Aseev LV., et al., 2015
Allosteric regulation of RNA-polymerase
  Regulator Function Promoter target of RNApol Growth Conditions Note Evidence Reference
  DksA-ppGpp inhibition rplVp nd   [GEA] [2]
Evidence: [GEA] Gene expression analysis
Reference(s): [2] Aseev LV., et al., 2015

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: forward
Evidence: [ICA] Inferred by computational analysis
Reference(s): [3] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -12.8 2282470 2282495 gatcacttacCTGTTGCTGGGTCGCCTGTAGCAGGattaatttaa
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"