RegulonDB RegulonDB 10.9: Operon Form

msrB operon and associated TUs in Escherichia coli K-12 genome

Name: msrB
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit       
Name: msrB
Gene(s): msrB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IC] Inferred by curator
[ICWHO] Inferred computationally without human oversight
Name: msrBp6
+1: 1862464
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 35
Sequence: agatcaagtttaggacaaaattttgccagttggtgttaatgttttgttagaatcagtcacGtaatgtgagcacgattaaag
                       -35                      -10         +1                   
Note(s): Huerta et al. identified a prediction of a possible transcription start site, located at bp -37 in relation to the start of the msrB gene Huerta AM,2003 Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.96. P-value: 1.033e-5
Evidence: [ICWHO]
Reference(s): [1] Bos J., et al., 2013
[2] Huerta AM., et al., 2003
[3] Salgado H, et al., 2012
sRNA Interaction TU
sRNA TU Regulated Function Binding Sites Regulatory Mechanism Evidence (Confirmed, Strong, Weak) Reference(s)
PosLeft PosRight Target sequence (mRNA)
small regulatory RNA RyhB msrB repressor 1862427 1862439 CAUUUGCUCACAU TRANSLATION-BLOCKING, MRNA-DEGRADATION [IDA], [IEP], [SM] [1]
small regulatory RNA RyhB msrB repressor 1862453 1862464 UGCUCACAUUAC TRANSLATION-BLOCKING, MRNA-DEGRADATION [IDA], [IEP], [SM] [1]