RegulonDB RegulonDB 10.9: Operon Form
   

yoaC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yoaC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: yoaC
Gene(s): yoaC   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: yoaCp1
+1: 1893966
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 167
Sequence: agcaactctggttttctttcttagctgaacaatctggttatagcgtgcggactgaccgttAaatttctccatcttactgga
                          -35                    -10        +1                   
Note(s): Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: -1.96. P-value: 2.123e-5
Evidence: [ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[CysB,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CysB-O-acetyl-L-serine activator yoaCp1 1893800 1893842 -145.5 agatattactGTTGATGCTTCTGCTAATTCATTATTTATATTTATAATTTCAAttttatctat nd [AIBSCS] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [AIBSCS] Automated inference based on similarity to consensus sequences


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Kawano Y., Ohtsu I., Takumi K., Tamakoshi A., Nonaka G., Funahashi E., Ihara M., Takagi H., 2015, Enhancement of L-cysteine production by disruption of yciW in Escherichia coli., J Biosci Bioeng 119(2):176-9

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