RegulonDB RegulonDB 11.2: Operon Form
   

hslJ operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: hslJ
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: hslJ
Gene(s): hslJ   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of the gene ydeI is increased when colicin (at 30 ng/ml) is added to the medium Kamen?ek S, ?gur-Bertok D,2013.
Evidence: [COMP-AINF] Inferred computationally without human oversight
Promoter
Name: hslJp
+1: 1441780
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 37
Sequence: ctgcattccaggggagctgattcagataatccccaatgacctttcatcctctattcttaaAatagtcctgagtcagaaact
                               -35                       -10+1                   
Evidence: [COMP-AINF]
[EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [1] Huerta AM., et al., 2003
[2] Jovanovic M., et al., 2003
TF binding sites (TFBSs)
[CysB,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CysB-O-acetyl-L-serine repressor hslJp 1441775 1441816 -16.0 agctgattcaGATAATCCCCAATGACCTTTCATCCTCTATTCTTAAAATAGTcctgagtcag nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2], [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences

 [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] Binding of purified proteins


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Jovanovic M., Lilic M., Savic DJ., Jovanovic G., 2003, The LysR-type transcriptional regulator CysB controls the repression of hslJ transcription in Escherichia coli., Microbiology 149(Pt 12):3449-59

 [3] Lilic M., Jovanovic M., Jovanovic G., Savic DJ., 2003, Identification of the CysB-regulated gene, hslJ, related to the Escherichia coli novobiocin resistance phenotype., FEMS Microbiol Lett 224(2):239-46

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