RegulonDB RegulonDB 11.1: Operon Form
   

grxB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: grxB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: grxB
Gene(s): grxB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
Promoter
Name: grxBp
+1: 1124103
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 49
Sequence: tagccagaaacgcgccgcgcgtcgtttgcttgaacgcgacgcctgatttgatactcccccCtgactccttcatactgaaag
                               -35                     -10  +1                   
Evidence: [COMP-AINF]
[COMP-AINF-POSITIONAL-IDENTIFICATION]
[COMP-HINF]
Reference(s): [1] Huerta AM., et al., 2003
Allosteric regulation of RNA-polymerase
  Regulator Function Promoter target of RNApol Growth Conditions Note Evidence Reference
  ppGpp activation grxBp nd   [EXP-IEP-GENE-EXPRESSION-ANALYSIS]
[EXP-IMP] 		[2]
Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
[EXP-IMP] Inferred from mutant phenotype
Reference(s): [2] Potamitou A., et al., 2002


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-AINF-POSITIONAL-IDENTIFICATION] Automated inference of promoter position

 [COMP-HINF] Inferred by a human based on computational evidence


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Potamitou A., Neubauer P., Holmgren A., Vlamis-Gardikas A., 2002, Expression of Escherichia coli glutaredoxin 2 is mainly regulated by ppGpp and sigmaS., J Biol Chem 277(20):17775-80

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