RegulonDB RegulonDB 10.9: Operon Form
   

sbcDC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: sbcDC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: sbcDC
Gene(s): sbcC, sbcD   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of the sbcDC operon is indirectly induced by the action of RpoS; this in some way suggests the presence of another regulatory system Darmon E,2007
Evidence: [ICWHO] Inferred computationally without human oversight
[PAGTSBP] Products of adjacent genes in the same biological process
Reference(s): [1] Darmon E., et al., 2007
Promoter
Name: sbcDp
+1: 416977
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 25
Sequence: tattgatttccgtggcgcagaaaaaagcaaatggcacatctgtttgggtataatcgcgccCatgctttttcgccagggaac
                          -35                    -10        +1                   
Note(s): We assigned a putative transcriptional start site to this promoter based on the observation that the majority of the promoters, whose transcriptional start sites were determined experimentally, present a distance of 6 nucleotides between the transcriptional start site and the -10 box 3550697.
Evidence: [HIPP]
[ICWHO]
Reference(s): [2] Huerta AM., et al., 2003
[3] Naom IS., et al., 1989
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote PhoB-phosphorylated repressor sbcDp 417061 417079 -93.0 tgcgtcagatTTATGACAGATTTATGAAAAgctcgtcgca nd [APIORCISFBSCS], [BPP], [GEA] [4]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
Evidence: [ICA] Inferred by computational analysis
Reference(s): [5] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.7 416967 416996 tggcacatctGTTTGGGTATAATCGCGCCCATGCTTTTTcgccagggaa
  anti-terminator -6.0 416990 417029 gttattgattTCCGTGGCGCAGAAAAAAGCAAATGGCACATCTGTTTGGgtataatcgc
  anti-anti-terminator -7.6 417018 417059 ttatgaaaagCTCGTCGCACATATCTTCAGGTTATTGATTTCCGTGGCGCAgaaaaaagca
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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