RegulonDB RegulonDB 10.10: Operon Form

gltI-sroC-gltJKL operon and associated TUs in Escherichia coli K-12 genome

Name: gltI-sroC-gltJKL
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: gltIJKL-sroC
Synonym(s): gltIJKL
Gene(s): gltL, gltK, gltJ, sroC, gltI   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of the gltI gene is repressed during the first 24 h after the induction of nitrogen starvation Switzer A, Burchell L, McQuail J, Wigneshweraraj S,2020.
Name: gltIp1
+1: 687896
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 149
Sequence: aataggctgattcaaggcatttacgggagaaaaaatcggctcaaacatgaagaaatgaaaTgactgagtcagccgagaaga
                            -35                       -10   +1                   
Evidence: [HIPP]
Reference(s): [1] Huerta AM., et al., 2003
[2] Stafford GP., et al., 2005
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FlhDC activator gltIp1 687935 687953 -47.5 cggtctaaatAGGCTGATTCAAGGCATTTacgggagaaa nd [GEA], [APIORCISFBSCS], [BPP] [2]
proximal FlhDC activator gltIp1 687950 687966 -62.0 aatggcgaagAAACGGTCTAAATAGGCtgattcaagg nd [GEA], [APIORCISFBSCS], [BPP] [2]

Transcription unit       
Name: gltI-sroC-gltJKL
Gene(s): gltL, gltK, gltJ, sroC, gltI   Genome Browser M3D Gene expression COLOMBOS
Reference(s): [3] Zimmer DP., et al., 2000
Name: gltIp2
+1: Unknown
Sigma Factor: Sigma54 Sigmulon
Evidence: [AIBSCS]
Reference(s): [4] Reitzer L., et al., 2001

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
Evidence: [ICA] Inferred by computational analysis
Reference(s): [5] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -21.3 686681 686716 aacaatcttcGAGGGTAGCAGTTAACGCTGCTACCCTCTTTTTTCtggagtagat
  anti-terminator -6.8 686704 686744 cgggcctgaaAACCGCAATACGCTGGGTAACAATCTTCGAGGGTAGCAGTtaacgctgct
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"