RegulonDB RegulonDB 10.9: Operon Form
   

xerD-dsbC-recJ-prfB-lysS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: xerD-dsbC-recJ-prfB-lysS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: dsbC
Gene(s): dsbC   Genome Browser M3D Gene expression COLOMBOS
Promoter
Name: dsbCp
+1: 3038834
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 12
Sequence: accgagcgtctgcggcaacttcatcaacagcatcacccgcgggcgtgatgtctgaaaagaAcgggaagatttatgaagaaa
                            -35                    -10      +1                   
Note(s):

Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Dartigalongue C., et al., 2001
[2] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CpxR-Phosphorylated activator dsbCp 3039184 3039198 -357.5 gtgccgttagGTGAAGAGGCGGTTTActggctggaa nd [APIORCISFBSCS], [GEA] [1]
remote CpxR-Phosphorylated activator dsbCp 3039219 3039233 -391.5 acgggtcattGGTAAAGGCAACAAAgagcgtctgg nd [APIORCISFBSCS], [GEA] [1]


Transcription unit       
Name: dsbC-recJ-prfB
Gene(s): prfB, recJ, dsbC   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for prfB and recJ . This structure could regulate the expression of the genes, as observed for hemL gene expression 31964733.
Evidence: [ITCR] Inferred through co-regulation
Reference(s): [3] Rhodius VA., et al., 2005
Promoter
Name: dsbCp2
+1: 3039633
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 811
Sequence: ggaaaaaaatctggctgaaaatacgttgaacgcttaccgtcgcgatctgtcaatgatggtGgagtggttgcatcaccgcgg
                            -35                     -10     +1                   
Note(s): This promoter appears to be weakly induced, compared with other induced genes, during the first 15 minutes following σE induction; after 15 minutes, it is drastically decreased. However, its mRNA appears to be very stable Lacoux C,2020.
Evidence: [AIPP]
[ICWHO]
[TIM]
Reference(s): [2] Huerta AM., et al., 2003
[3] Rhodius VA., et al., 2005


Transcription unit       
Name: xerD-dsbC-recJ
Gene(s): recJ, dsbC, xerD   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ITCR] Inferred through co-regulation
Reference(s): [4] Nonaka G., et al., 2006
Promoter
Name: xerDp2
+1: 3039851
Sigma Factor: Sigma32 Sigmulon
Distance from start of the gene: 108
Sequence: ttctgccgccatttcggtgtaacaggtgctggaaccgtaaaaaagacccatattcataacGtaagcttctcgattctgctg
                              -35             -10           +1                   
Evidence: [HIPP]
[ICWHO]
[IDA]
Reference(s): [2] Huerta AM., et al., 2003
[4] Nonaka G., et al., 2006


Transcription unit       
Name: xerD-dsbC-recJ
Gene(s): recJ, dsbC, xerD   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ITCR] Inferred through co-regulation
Reference(s): [4] Nonaka G., et al., 2006
Promoter
Name: xerDp
+1: 3039851
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 108
Sequence: ttctgccgccatttcggtgtaacaggtgctggaaccgtaaaaaagacccatattcataacGtaagcttctcgattctgctg
                          -35                    -10        +1                   
Evidence: [HIPP]
[ICWHO]
[IDA]
Reference(s): [2] Huerta AM., et al., 2003
[4] Nonaka G., et al., 2006


Transcription unit       
Name: xerD
Gene(s): xerD   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Transcription unit       





RegulonDB