RegulonDB RegulonDB 11.1: Operon Form
   

nsrR-rnr-rlmB-yjfIJ operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: nsrR-rnr-rlmB-yjfIJ
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: nsrR-rnr-rlmB-yjfI
Gene(s): nsrR, rnr, rlmB, yjfI   Genome Browser M3D Gene expression COLOMBOS
Note(s): The nsrRp promoter is strong, and its nsrR mRNA is translated inefficiently. Translation of nsrR initiates with a GUG start codon, which is 2- to 3-fold less efficient in translation initiation than the more commonly used AUG. Conversion of this start codon from the wild-type GUG to AUG increased the efficiency of translation of nsrR mRNA and the abundance of NsrR Chhabra S,2015
Evidence: [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Cairrao F., et al., 2003
Promoter
Name: nsrRp
+1: 4406044
Distance from start of the gene: 146
Sequence: aattctggtacgcctggcagatattttgcctgccgggcgaacagtgtgatacattgctgtGtcgggtaagccattacgcta
Evidence: [EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [1] Cairrao F., et al., 2003


Transcription unit       
Name: yjfIJ
Gene(s): yjfI, yjfJ   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight


Evidence    

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping


Reference(s)    

 [1] Cairrao F., Cruz A., Mori H., Arraiano CM., 2003, Cold shock induction of RNase R and its role in the maturation of the quality control mediator SsrA/tmRNA., Mol Microbiol 50(4):1349-60

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