RegulonDB RegulonDB 11.2: Operon Form
   

preTA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: preTA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: preTA
Synonym(s): yeiTA
Gene(s): preT, preA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
[IC-ADJ-GENES-SAME-BIO-PROCESS] Products of adjacent genes in the same biological process
Reference(s): [1] Mihara H., et al., 2008
Promoter
Name: preTp
+1: 2233989
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 44
Sequence: atcttttcacagtttaaattcccccgcacgcttagccttaatatcagtacattattatttActaaacgctcgccttaatta
Note(s): A putative promoter for the yeiTA operon has been identified 11 bp downstream Mihara H,2008of that reported by Gama et al. (2008) Mendoza-Vargas A,2009
Evidence: [COMP-HINF]
[EXP-IDA-HPT-TRANSCR-INIT-M-RACE-MAP]
Reference(s): [2] Mendoza-Vargas A., et al., 2009
[1] Mihara H., et al., 2008
TF binding sites (TFBSs)
[CRP,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cyclic-AMP activator preTp 2233921 2233943 -57.5 aaccgcagctATTTGTGAATCTTTTCACAGTTTaaattccccc nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] W [1], [3]


Evidence    

 [COMP-HINF] Inferred by a human based on computational evidence

 [EXP-IDA-HPT-TRANSCR-INIT-M-RACE-MAP] High-throughput transcription initiation mapping

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences


Reference(s)    

 [1] Mihara H., Hidese R., Yamane M., Kurihara T., Esaki N., 2008, The iscS gene deficiency affects the expression of pyrimidine metabolism genes., Biochem Biophys Res Commun 372(3):407-11

 [2] Mendoza-Vargas A., Olvera L., Olvera M., Grande R., Vega-Alvarado L., Taboada B., Jimenez-Jacinto V., Salgado H., Juarez K., Contreras-Moreira B., Huerta AM., Collado-Vides J., Morett E., 2009, Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli., PLoS One 4(10):e7526

 [3] Tsai MJ., Wang JR., Yang CD., Kao KC., Huang WL., Huang HY., Tseng CP., Huang HD., Ho SY., 2018, PredCRP: predicting and analysing the regulatory roles of CRP from its binding sites in Escherichia coli., Sci Rep 8(1):951

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