RegulonDB RegulonDB 11.1: Operon Form
   

mcaS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mcaS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: mcaS
Synonym(s): isrA
Gene(s): mcaS   Genome Browser M3D Gene expression COLOMBOS
Note(s): The RNA produced by the mcaS gene has been observed mainly in the poles of the cell Kannaiah S, Livny J, Amster-Choder O,2019.
Evidence: [COMP-AINF-SINGLE-DIRECTON] Automated inference that a single-gene directon is a transcription unit
[EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Thomason MK., et al., 2012
Promoter
Name: mcaSp
+1: 1405751
Distance from start of the gene: 0
Sequence: cgtgaaatctgtcactgaagaaaattggcaactaaaggttaaaaccgttataacacagtcAccggcgcagaggagacaatg
Evidence: [EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [1] Thomason MK., et al., 2012
TF binding sites (TFBSs)
[CRP,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cyclic-AMP activator mcaSp 1405793 1405815 -52.5 gtaacttataTTTTCGTGAAATCTGTCACTGAAgaaaattggc nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [1]


Evidence    

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [COMP-HINF-SIMILAR-TO-CONSENSUS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] Binding of purified proteins


Reference(s)    

 [1] Thomason MK., Fontaine F., De Lay N., Storz G., 2012, A small RNA that regulates motility and biofilm formation in response to changes in nutrient availability in Escherichia coli., Mol Microbiol 84(1):17-35

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