RegulonDB RegulonDB 10.8: Operon Form
   

acrZ operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: acrZ
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: acrZ
Gene(s): acrZ   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: acrZp
+1: 794751
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 22
Sequence: cgcaaagctgaccgcacaaaaggggagtgcttttctgtgcttagcggttagaatagtctcAtgactatatctggagttgac
                                                 -10        +1                   
Evidence: [TIM]
Reference(s): [1] Hobbs EC., et al., 2012
TF binding sites (TFBSs)
[MarA,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal MarA activator acrZp 794701 794720 -40.5 cgcaaagctgACCGCACAAAAGGGGAGTGCttttctgtgc nd [CV(GEA/ROMA)], [GEA], [IHBCE] [1]
[Rob,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Rob activator acrZp 794701 794720 -40.5 cgcaaagctgACCGCACAAAAGGGGAGTGCttttctgtgc nd [CV(GEA/ROMA)], [GEA], [IHBCE] [1]
[SoxS,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal SoxS activator acrZp 794701 794720 -40.5 cgcaaagctgACCGCACAAAAGGGGAGTGCttttctgtgc nd [CV(GEA/ROMA)], [GEA], [IHBCE] [1]


Evidence    

 [TIM] Transcription initiation mapping

 [CV(GEA/ROMA)] cross validation(GEA/ROMA)

 [GEA] Gene expression analysis

 [IHBCE] Inferred by a human based on computational evidence


Reference(s)    

 [1] Hobbs EC., Yin X., Paul BJ., Astarita JL., Storz G., 2012, Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance., Proc Natl Acad Sci U S A 109(41):16696-701

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