RegulonDB RegulonDB 10.8: Operon Form
   

dgcC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: dgcC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: adrA
Synonym(s): yaiC
Gene(s): dgcC   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Brombacher E., et al., 2003
Promoter
Name: adrAp
+1: 403687
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 16
Sequence: tacgaaaatggctcacccgaaatatcatacttctgcctttagctccgtctctataatttgGgaaaattgtttctgaatgtt
                               -35             -10          +1                   
Note(s): The adrAp promoter has a -10 box perfectly matching the boxes for σ70 promoters, but it does not have a -35 box, which is consistent with the fact that it is a promoter that is activated Brombacher E,2003 .
Evidence: [HIPP]
[TIM]
Reference(s): [1] Brombacher E., et al., 2003
[2] Weber H., et al., 2006
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CsgD activator adrAp 403615 403629 -65.5 ctgatagtgcTAACGGGTGAGCTACgaaaatggct nd [AIBSCS], [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(CHIP-SV/SM)], [CV(GEA/ROMA)], [CV(GEA/ROMA/SM)], [GEA], [SM] [1], [3]
proximal CsgD2 activator adrAp 403635 403645 -47.0 gctacgaaaaTGGCTCACCCGaaatatcata nd [AIBSCS], [CV(CHIP-SV/GEA/ROMA)], [CV(CHIP-SV/SM)], [CV(GEA/ROMA)], [CV(GEA/ROMA/SM)], [GEA], [SM] [1]
Note(s): 2The CsgD protein is bound to two sites (-47 and -64) upstream of the adrAp promoter. Together, these sites form an inverted repeat, suggesting that CsgD binds to this region as a dimer. In other regulatory regions, the CsgD protein binds to just one site Brombacher E,2003.2The CsgD protein is bound to two sites (-47 and -64) upstream of the adrAp promoter. Together, these sites form an inverted repeat, suggesting that CsgD binds to this region as a dimer. In other regulatory regions, the CsgD protein binds to just one site Brombacher E,2003.





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