RegulonDB RegulonDB 11.1: Operon Form

cmoM-mukFEB operon and associated TUs in Escherichia coli K-12 genome

Name: cmoM-mukFEB
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: smtA-mukFEB
Gene(s): cmoM, mukF, mukE, mukB   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for mukE . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020.
Evidence: [EXP-IEP] Inferred from expression pattern
[EXP-IEP-COREGULATION] Inferred through co-regulation
Reference(s): [1] Yamanaka K., et al., 1995
[2] Yamanaka K., et al., 1996
Name: cmoMp
+1: 973404
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 133
Sequence: acatcagcggaagtggcagcaacatattgccaatcacttttttcagtgtaaaaagcatccTttctggttccttttttaacc
                           -35                   -10        +1                   
Evidence: [COMP-AINF]
Reference(s): [3] Huerta AM., et al., 2003
[1] Yamanaka K., et al., 1995
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd H-NS activator cmoMp nd nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS] W nd