RegulonDB RegulonDB 10.8: Operon Form
   

cecR-ybhGFSR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: cecR-ybhGFSR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: cecR-ybhGFSR
Gene(s): ybhR, ybhS, ybhF, ybhG, cecR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: cecRp
+1: 830669
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 26
Sequence: cgttgctaaaattcttagccatactggacaactcccctatggagtcataatcttaatcaaTcatttgattaagaatggact
                              -35                 -10       +1                   
Evidence: [HIPP]
Reference(s): [1] Yamanaka Y., et al., 2016
TF binding sites (TFBSs)
[CecR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CecR repressor cecRp 830658 830678 2.5 gagtcataatCTTAATCAATCATTTGATTAAgaatggactg nd [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/GS)], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/GS)], [CV(GEA/ROMA)], [GEA], [GS] [1], [2]


Evidence    

 [HIPP] Human inference of promoter position

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [BPP] Binding of purified proteins

 [CV(CHIP-SV/GEA/GS)] cross validation(CHIP-SV/GEA/GS)

 [CV(CHIP-SV/GEA/ROMA)] cross validation(CHIP-SV/GEA/ROMA)

 [CV(GEA/GS)] cross validation(GEA/GS)

 [CV(GEA/ROMA)] cross validation(GEA/ROMA)

 [GEA] Gene expression analysis

 [GS] genomic SELEX


Reference(s)    

 [1] Yamanaka Y., Shimada T., Yamamoto K., Ishihama A., 2016, Transcription factor CecR (YbiH) regulates a set of genes affecting the sensitivity of Escherichia coli against cefoperazone and chloramphenicol., Microbiology 162(7):1253-64

 [2] Shimada T., Ogasawara H., Ishihama A., 2018, Single-target regulators form a minor group of transcription factors in Escherichia coli K-12., Nucleic Acids Res 46(8):3921-3936

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