RegulonDB RegulonDB 10.9: Operon Form
   

btsT operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: btsT
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: btsT
Synonym(s): yjiY
Gene(s): btsT   Genome Browser M3D Gene expression COLOMBOS
Note(s): The btsT gene belongs to the CstA superfamily of transporters, and it is strongly induced at the onset of the stationary growth phase, which requires cAMP and the cAMP receptor protein CRP Kraxenberger T,2012 btsT was expressed after growth on amino acids or peptides as carbon sources Kraxenberger T,2012
A functional link between the two systems provides positive feedback between YpdA/YhjX and btsT transcription, while yhjX is negatively regulated by BtsS/BtsT activity Behr S,2014. 28796832
A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for btsT. This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: yjiYp
+1: 4591367
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 88
Sequence: aaataaccactcagttatttaccttactttacgcgcgcgtaactctggcaacatcactacAggatagcggtcaatttacct
                           -35                -10           +1                   
Evidence: [TIM]
Reference(s): [1] Kraxenberger T., et al., 2012
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal BtsR-Phosphorylated activator yjiYp 4591415 4591444 -62.0 ccgcaaaactGACCGCTTACATCCCTAAAATAACCACTCAgttatttacc nd [AIBSPD], [BPP], [GEA], [SM] [1], [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CRP-cAMP activator yjiYp 4591489 4591511 -132.5 tcacaatataAATATGTGATATGAATCACATATttatcgtcac nd [AIBSCS], [GEA], [SM] [1]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.5 4591306 4591326 aacgcaaaccTAGAACGGCTTCGGCCAACTattaatcaat
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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