RegulonDB RegulonDB 10.9:Regulon Page
   

IHF DNA-binding transcriptional dual regulator

Synonyms: IHF
Summary:
IHF, "Integration host factor," is a global regulatory protein that helps to maintain DNA architecture. It binds and bends DNA at specific sites. IHF plays a role in DNA supercoiling and DNA duplex destabilization and affects processes such as DNA replication, recombination, and the expression of many genes [38] IHF is highly abundant in the cell. Its total intracellular concentration varies with growth rate and is higher in exponential phase, with 6,000 dimers per cell, than in stationary phase (3,000 dimers per cell) [] IHF acts mostly as an accessory factor, stabilizing a correct nucleoprotein complex. For example, IHF was originally found to be required for the site-specific recombination of phage λ with the chromosome [] For this, IHF stabilizes the bending of the DNA to facilitate binding of the bivalent integrase molecules [] There are two distinct DNA-bending steps during site recognition by IHF.
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Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
IHF Functional   [APPH], [GEA], [IEP], [IMP] [1], [2], [3], [4], [5], [6], [7]
Connectivity class: Global Regulator
Gene name: ihfA
  Genome position: 1795253-1795552
  Length: 300 bp / 99 aa
Operon name: thrS-infC-rpmI-rplT-pheMST-ihfA
TU(s) encoding the TF:
Transcription unit        Promoter
ihfA
ihfAp4
pheMST-ihfA
pheMp
thrS-infC-rpmI-rplT-pheMST-ihfA
thrSp
Gene name: ihfB
  Genome position: 963828-964112
  Length: 285 bp / 94 aa
Operon name: cmk-rpsA-ihfB
TU(s) encoding the TF:
Transcription unit        Promoter
ihfB
ihfBp
ihfB
ihfBp2
rpsA-ihfB
rpsAp1
rpsA-ihfB
rpsAp3


Regulon       
Regulated gene(s) aceA, aceB, aceK, acs, actP, adiA, amiA, atoA, atoB, atoD, atoE, carA, carB, csgD, csgE, csgF, csgG, csrB, cysG, cysH, cysI, cysJ, dcuD, dmsA, dmsB, dmsC, dppA, dppB, dppC, dppD, dppF, dps, dusB, envZ, fhlA, fimA, fimB, fimC, fimD, fimF, fimG, fimH, fimI, fis, flhC, flhD, fliA, fliZ, fnr, focA, folA, gcd, glcA, glcB, glcD, glcE, glcF, glcG, glmY, glnH, glnP, glnQ, glpQ, glpT, gltA,
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Multifun term(s) of regulated gene(s) MultiFun Term (List of genes associated to the multifun term)
membrane (43)
anaerobic respiration (35)
carbon compounds (21)
Transcription related (19)
aerobic respiration (16)
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Regulated operon(s) aceBAK, acs-yjcH-actP, adiA, amiA-hemF, atoDAEB, bdm-sra, carAB, cmk-rpsA-ihfB, csgDEFG, csrB, cysJIH, dcuD, dmsABC, dppABCDF, dps, dusB-fis, fimAICDFGH, fimB, flhDC, fliAZ-tcyJ, fnr, focA-pflB, folA, gcd, glcDEFGBA, glmY, glnHPQ, glpTQ, gltA, gltBDF, hemA-prfA-prmC, hipBA, hpt, hycABCDEFGHI, hypABCDE-fhlA, ibpAB, ilvLXGMEDA, micF, mtr, narGHJI, narK, ndh, nirBDC-cysG, nmpC, norVW, nrfABCDEFG, nuoABCEFGHIJKLMN, ompC, ompF, ompR-envZ, osmE, osmY, paaABCDEFGHIJK, paaZ, patA, plaR, proVWX, pspABCDE, pspG, pstSCAB-phoU, rpoH, rseD-rpoE-rseABC, rtcBA, sdhCDAB-sucABCD-sdhX, sodA,
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First gene in the operon(s) aceB, acs, adiA, amiA, atoD, carA, csgD, csrB, cysJ, dcuD, dmsA, dppA, dps, dusB, fimA, fimB, flhD, fliA, fnr, focA, folA, gcd, glcD, glmY, glnH, glpT, gltA, gltB, hemA, hemF, hipB, hpt, hycA, hypA, ibpB, ihfA, ihfB, ilvL, micF, mtr, narG, narK, ndh, nirB, norV, nrfA, nuoA, ompC, ompF, ompR, osmE, osmY, paaA, paaZ, patA, plaR, proV, pspA, pspG, pstS, rseD, rpoH, rtcB, sodA, sodB,
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Simple and complex regulons AcrR,CRP,FliZ,Fur,H-NS,HdfR,IHF,LrhA,MatA,OmpR,QseB,RcsAB,YjjQ
AcrR,H-NS,HU,IHF,Lrp,MarA,OmpR,Rob,SoxS
AdiY,ArgR,CRP,FNR,Fur,GadE,HdfR,IHF,Lrp,Nac
AdiY,H-NS,IHF
ArcA,CRP,Cra,IHF,IclR
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Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)
[IHF,+](58)
[IHF,-](44)


Transcription factor regulation    


Transcription factor binding sites (TFBSs) arrangements
      

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence LeftPos RightPos Evidence (Confirmed, Strong, Weak) References
  IHF activator aceBp Sigma70 -159.0 -235.0 aceB, aceA, aceK
tcgttaagcgATTCAGCACCTTACctcaggcacc
4215237 4215249 [BPP], [GEA] [8]
  IHF activator aceBp Sigma70 -72.0 -148.0 aceB, aceA, aceK
ttcatattgtTATCAACAAGTTATcaagtatttt
4215324 4215336 [BPP], [GEA] [8]
  IHF repressor acsp Sigma38 -225.0 -245.0 acs, yjcH, actP
tctttaatcaATTGTAAGTGCATGtaaaatacca
4287610 4287622 [BPP], [GEA] [9], [10]
  IHF repressor acsp Sigma38 -180.0 -200.0 acs, yjcH, actP
gtcagtatctTCCTCTTTTTCAACagcatgcata
4287565 4287577 [AIBSCS], [BPP], [GEA] [11]
  IHF repressor acsp Sigma38 -153.0 -173.0 acs, yjcH, actP
atgcataactGCATGTTCCTCAAAgaattaatca
4287538 4287550 [AIBSCS], [BPP], [GEA], [SM] [11], [12]
  IHF repressor acsp1 Sigma70 -21.0 -245.0 acs, yjcH, actP
tctttaatcaATTGTAAGTGCATGtaaaatacca
4287610 4287622 [BPP], [GEA] [9]
  IHF repressor acsp2 Sigma70 -225.0 -245.0 acs, yjcH, actP
tctttaatcaATTGTAAGTGCATGtaaaatacca
4287610 4287622 [BPP], [GEA] [9], [10]
  IHF repressor acsp2 Sigma70 -180.0 -200.0 acs, yjcH, actP
gtcagtatctTCCTCTTTTTCAACagcatgcata
4287565 4287577 [AIBSCS], [BPP], [GEA] [11]
  IHF repressor acsp2 Sigma70 -153.0 -173.0 acs, yjcH, actP
atgcataactGCATGTTCCTCAAAgaattaatca
4287538 4287550 [AIBSCS], [BPP], [GEA], [SM] [11], [12]
  IHF activator adiAp Sigma70 nd nd adiA nd nd [BPP], [GEA], [IGI] [13]
  IHF repressor amiAp Sigma70 20.5 -91.5 amiA, hemF
tgtcaactatTGAAATGAAAAGTAaaacaattct
2552254 2552266 [APIORCISFBSCS] [14]
  IHF activator atoDp Sigma54 -57.0 -92.0 atoD, atoA, atoE, atoB
cccttcatatTCAATTAGTTAAATaactaaatcc
2323349 2323361 [APIORCISFBSCS], [GEA] [15]
  IHF activator atoDp Sigma54 -32.0 -67.0 atoD, atoA, atoE, atoB
actaaatccaATAATCTCATTCTGgcactcccct
2323374 2323386 [APIORCISFBSCS], [GEA], [SM] [15]
  IHF activator carAp1 Sigma70 -305.0 -405.0 carA, carB
atttaatttaTTGATTATAAAGGGctttaatttt
29240 29252 [APIORCISFBSCS], [BCE], [BPP], [GEA], [SM] [16], [17]
  IHF repressor carAp1 Sigma70 -305.0 -405.0 carA, carB
atttaatttaTTGATTATAAAGGGctttaatttt
29240 29252 [APIORCISFBSCS], [BCE], [BPP], [GEA], [SM] [16], [17]
  IHF activator csgDp1 Sigma70 -173.5 -321.5 csgD, csgE, csgF, csgG
aaatatttttTATATGCATTATTAGTAAGTTATCACCATTTgtatgatttt
1103503 1103533 [BPP], [GEA] [18]
  IHF activator csgDp1 Sigma70 -66.5 -214.5 csgD, csgE, csgF, csgG
catttctaaaCTTAATAAAACCTTAAGGTTAACATTTTAATATAACGAGTTACATTTAGTTACATGTTTAAcacttgattt
1103381 1103441 [BPP], [GEA] [18]
  IHF activator csgDp3 Sigma38 -173.5 -321.5 csgD, csgE, csgF, csgG
aaatatttttTATATGCATTATTAGTAAGTTATCACCATTTgtatgatttt
1103503 1103533 [BPP], [GEA] [18]
  IHF activator csgDp3 Sigma38 -66.5 -214.5 csgD, csgE, csgF, csgG
catttctaaaCTTAATAAAACCTTAAGGTTAACATTTTAATATAACGAGTTACATTTAGTTACATGTTTAAcacttgattt
1103381 1103441 [BPP], [GEA] [18]
  IHF activator csrBp Sigma70 -99.0 -99.0 csrB
ttttcatttaAAATCAAAATGTTGattgttaatt
2924617 2924629 [AIBSCS], [GEA] [19]
  IHF activator cysJp Sigma70 -124.0 -190.0 cysJ, cysI, cysH
ggctaaattcATTTGTTTTTCATTaggttggtta
2892082 2892094 [BPP], [GEA] [20]
  IHF activator dcuDp2 Sigma54 -44.0 -330.0 dcuD
acatcctatcACAGGATTGAAAGTaggggaaaat
3374533 3374545 [APIORCISFBSCS]
  IHF repressor dmsAp2 nd -22.0 -103.0 dmsA, dmsB, dmsC
tctctttgatTTTCAAATTATTCGatgtatacaa
940850 940862 [APIORCISFBSCS], [BPP], [GEA] [21]
  IHF activator dppAp Sigma70 1848.0 1683.0 dppA, dppB, dppC, dppD, dppF
caggcctacgAAAATTCTGCAATGtattgaattt
3706017 3706029 [BCE]
  IHF activator dpsp Sigma70 -98.5 -137.5 dps
atatatctaaCTCATTGAATCTTTattagttttg
849042 849054 [APIORCISFBSCS]
  IHF activator dpsp2 Sigma38 -98.5 -137.5 dps
atatatctaaCTCATTGAATCTTTattagttttg
849042 849054 [APIORCISFBSCS]
  IHF activator dusBp Sigma70 -114.0 -148.0 dusB, fis
tttctaatatGATGATTTTTATGAgtaattatcg
3410126 3410138 [APIORCISFBSCS], [BPP], [GEA], [SM] [22], [23]
  IHF activator fimAp Sigma70 -52.0 -473.0 fimA, fimI, fimC, fimD, fimF, fimG, fimH
aggtttgattTAACTTATTGATAAtaaagttaaa
4542636 4542648 [APIORCISFBSCS], [GEA] [24], [25], [26], [27]
  IHF activator fimAp Sigma70 77.0 -345.0 fimA, fimI, fimC, fimD, fimF, fimG, fimH
aaaaagcatcTAACTGTTTGATATgtaaattatt
4542764 4542776 [APIORCISFBSCS], [GEA] [24], [25], [26], [27]
  IHF activator fimBp2 nd -576.0 -866.0 fimB
agatcttagtTTAACTATTTGTTTtataaataat
4540085 4540097 [APIORCISFBSCS], [BPP], [SM] [28]
  IHF repressor flhDp Sigma70 -92.0 -290.0 flhD, flhC
cccatttatgTTAAGTAATTGAGTgttttgtgtg
1978481 1978493 [APIORCISFBSCS] [29]
  IHF repressor fliAp1 Sigma70 -202.5 -232.5 fliA, fliZ, tcyJ
tacaagttgaATTGCAATTTATTGAATttgcacattt
2002014 2002030 [GEA], [IHBCE], [SM] [30]
  IHF repressor fliAp1 Sigma70 -186.5 -216.5 fliA, fliZ, tcyJ
atttattgaaTTTGCACATTTTTGTAGgccggataag
2001998 2002014 [GEA], [IHBCE], [SM] [30]
  IHF activator fnrp Sigma70 -104.0 -130.0 fnr
cccttaacaaCTTAAGGGTTTTCAAatagatagac
1399649 1399663 [BPP], [GEA], [SM] [31]
  IHF activator focAp1 Sigma70 -112.5 -139.5 focA, pflB
tatttttattTGGATAATCAAATAtttactccgt
954599 954611 [APIORCISFBSCS], [BCE], [BPP], [GEA], [SM]
  IHF activator folAp Sigma70 -65.0 -89.0 folA
tcgccagcagAATATAAAATTTTCctcaacatca
49728 49740 [APIORCISFBSCS], [GEA] [32]
  IHF activator gcdp1 Sigma70 -73.0 -111.0 gcd
agtataccagTAAAACTATTCATTcgcggaatct
141330 141342 [APIORCISFBSCS], [GEA], [SM] [33]
  IHF activator glcDp Sigma70 -107.0 -162.0 glcD, glcE, glcF, glcG, glcB, glcA
gattatgttaCATCAATTTAACATtgagttaacc
3128177 3128189 [BCE], [GEA] [34]
  IHF activator glmYp1 Sigma54 -169.0 -169.0 glmY
ggcgacacttAACTCATTGATTTTaatattatct
2691503 2691515 [APIORCISFBSCS], [BPP], [GEA], [SM] [35], [36]
  IHF activator glmYp1 Sigma54 -52.0 -52.0 glmY
aagcaacgtaTAATCAGTACGTTAccaaactatt
2691386 2691398 [APIORCISFBSCS], [BPP], [GEA] [35]
  IHF activator glnHp2 Sigma54 -152.0 -195.0 glnH, glnP, glnQ
ttacgctaaaTAATCACTGTGTTGagtgcacaat
848193 848205 [APIORCISFBSCS] [37], [38]
  IHF activator glnHp2 Sigma54 -47.0 -90.0 glnH, glnP, glnQ
ttttgccgcaTCTCGAAAAATCAAggagttgcaa
848088 848100 [APIORCISFBSCS], [BPP], [SM] [37], [39]
  IHF repressor glpTQp Sigma70 35.0 -43.0 glpT, glpQ
gttctctcacTGAATCAGGCTGTTaatcataaat
2352411 2352423 [APIORCISFBSCS], [BPP], [GEA] [40]
  IHF repressor glpTQp Sigma70 202.0 125.0 glpT, glpQ
tggctatgcgGCTTACTATTTGGTtcgtaagaac
2352244 2352256 [APIORCISFBSCS], [BPP], [GEA] [40]
  IHF activator gltAp1 Sigma70 -70.0 -369.0 gltA
atttaattttTAATCATCTAATTTgacaatcatt
754831 754843 [AIBSCS], [BCE], [GEA] [41], [42], [43]
  IHF activator gltBp Sigma70 -89.0 -305.0 gltB, gltD, gltF
tccattttaaTTTCAGTCATTTAAtaaagaattt
3354414 3354426 [BPP], [GEA] [44], [45]
  IHF activator gltBp Sigma70 -85.0 -301.0 gltB, gltD, gltF
ttttaatttcAGTCATTTAATAAAgaattttgcg
3354418 3354430 [BPP], [GEA] [44], [45]
  IHF activator gltBp2 Sigma38 -89.0 -305.0 gltB, gltD, gltF
tccattttaaTTTCAGTCATTTAAtaaagaattt
3354414 3354426 [BPP], [GEA] [44], [45]
  IHF activator gltBp2 Sigma38 -85.0 -301.0 gltB, gltD, gltF
ttttaatttcAGTCATTTAATAAAgaattttgcg
3354418 3354430 [BPP], [GEA] [44], [45]
  IHF activator hemAp1 Sigma70 nd nd hemA, prfA, prmC nd nd [BPP], [GEA], [IGI] [46]
  IHF repressor hemFp Sigma70 8.0 -13.0 hemF
agaaagcacaTTCGAAAAAGCGATaagttatgaa
2553206 2553218 [APIORCISFBSCS] [14]
  IHF activator hipBp Sigma70 -117.0 -157.0 hipB, hipA
ttcaaacggcGCATCAACGCCTTAtttaaatcct
1592593 1592605 [APIORCISFBSCS] [47]
  IHF repressor hptp Sigma70 -24.0 -95.0 hpt
agattccgcgAATGAATAGTTTTActggtatact
141330 141342 [APIORCISFBSCS], [GEA], [SM] [33]
  IHF activator hycAp Sigma54 -38.5 -64.5 hycA, hycB, hycC, hycD, hycE, hycF, hycG, hycH, hycI
aatctctttaATAACAATAAATTAaaagttggca
2850493 2850505 [APIORCISFBSCS], [BPP], [GEA] [48]
  IHF activator hypAp Sigma54 -127.5 -147.5 hypA, hypB, hypC, hypD, hypE, fhlA
tgccaactttTAATTTATTGTTATtaaagagatt
2850493 2850505 [APIORCISFBSCS], [BPP], [GEA]
  IHF activator ibpBp Sigma54 -31.0 -115.0 ibpB
cgccgtatcgAAATCAACTAATTCcctaaggccg
3867006 3867018 [AIBSCS]
  IHF repressor ihfAp4 Sigma38 -47.0 -216.0 ihfA
agcggatattTTATCCGAATGTAAgaaagttggc
1795762 1795774 [APIORCISFBSCS], [BPP] [1], [49]
  IHF repressor ihfAp4 Sigma38 -21.0 -190.0 ihfA
aagttggcgtAAATCAGGTAGTTGgcgtaaactt
1795736 1795748 [APIORCISFBSCS], [BPP] [1], [49]
  IHF repressor ihfAp4 Sigma38 54.0 -116.0 ihfA
aagagcctcgCCATAAGCCTGATCctgcaagata
1795662 1795674 [APIORCISFBSCS], [BPP] [1], [49]
  IHF repressor ihfBp Sigma70 -320.0 -399.0 ihfB
cgttgaaggtTACCTGCGTGCTTCtgaagcatcc
963423 963435 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp Sigma70 -304.0 -383.0 ihfB
cgtgcttctgAAGCATCCCGTGACcgcgttgaag
963439 963451 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp Sigma70 -207.0 -286.0 ihfB
aaaaccgcgcAATCAGCCTGTCTGttcgtgcgaa
963536 963548 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp Sigma70 -157.0 -236.0 ihfB
aaagatgcaaTCGCAACTGTTAACaaacaggaag
963586 963598 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp Sigma70 -77.0 -156.0 ihfB
taaaggcgagTAATTCTCTGACTCttcgggattt
963666 963678 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp Sigma70 -2.0 -81.0 ihfB
ttcgtcctgtAATCAAGCACTAAGggcggctacg
963741 963753 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -320.0 -399.0 ihfB
cgttgaaggtTACCTGCGTGCTTCtgaagcatcc
963423 963435 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -304.0 -383.0 ihfB
cgtgcttctgAAGCATCCCGTGACcgcgttgaag
963439 963451 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -207.0 -286.0 ihfB
aaaaccgcgcAATCAGCCTGTCTGttcgtgcgaa
963536 963548 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -157.0 -236.0 ihfB
aaagatgcaaTCGCAACTGTTAACaaacaggaag
963586 963598 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -77.0 -156.0 ihfB
taaaggcgagTAATTCTCTGACTCttcgggattt
963666 963678 [BPP], [GEA] [1], [49]
  IHF repressor ihfBp2 Sigma38 -2.0 -81.0 ihfB
ttcgtcctgtAATCAAGCACTAAGggcggctacg
963741 963753 [BPP], [GEA] [1], [49]
  IHF repressor ilvLp1 Sigma70 -17.0 -121.0 ilvL, ilvX, ilvG, ilvM, ilvE, ilvD, ilvA
tatttttaaaAAACAACAATTTATattgaaatta
3950195 3950207 [BPP], [GEA], [SM] [50]
  IHF repressor ilvLp1 Sigma70 210.0 106.0 ilvL, ilvX, ilvG, ilvM, ilvE, ilvD, ilvA
aaaggcttagAGATCAAGCCTTAAcgaactaaga
3950421 3950433 [APIORCISFBSCS], [BPP], [GEA] [50]
  IHF activator ilvLp2 Sigma70 -89.0 -121.0 ilvL, ilvX, ilvG, ilvM, ilvE, ilvD, ilvA
tatttttaaaAAACAACAATTTATattgaaatta
3950195 3950207 [BPP], [GEA], [SM] [51], [52], [53], [54]
  IHF activator ilvLp2 Sigma70 138.0 106.0 ilvL, ilvX, ilvG, ilvM, ilvE, ilvD, ilvA
aaaggcttagAGATCAAGCCTTAAcgaactaaga
3950421 3950433 [APIORCISFBSCS], [BPP], [GEA] [51], [54]
  IHF repressor micFp Sigma70 -72.0 -72.0 micF
tcaaggttaaAATCAATAACTTATtcttaagtat
2313006 2313018 [APIORCISFBSCS], [BCE], [BPP], [GEA] [55]
  IHF repressor micFp2 Sigma38 -72.0 -72.0 micF
tcaaggttaaAATCAATAACTTATtcttaagtat
2313006 2313018 [APIORCISFBSCS], [BCE], [BPP], [GEA] [55]
  IHF repressor mtrp2 Sigma70 nd nd mtr nd nd [BPP], [GEA], [IGI] [56]
  IHF activator narGp Sigma70 -125.0 -182.0 narG, narH, narJ, narI
aaacgtcttaATTTACAGTCTGTTatgtggtggc
1279676 1279688 [APIORCISFBSCS], [BCE], [BPP], [GEA] [57], [58], [59]
  IHF activator narKp1 Sigma70 -130.0 -155.0 narK
ttttacagcaCCGTGAAAAATCTCataattttta
1277796 1277808 [BPP], [GEA] [60], [61]
  IHF repressor ndhp Sigma70 -58.0 -151.0 ndh
cttttcagcaACAAAACTTGATTAacatcaattt
1165928 1165940 [APIORCISFBSCS], [BCE], [BPP], [GEA] [62]
  IHF repressor ndhp Sigma70 -17.0 -110.0 ndh
accaatgcacCATTCATGTTATTCtcaatagcga
1165969 1165981 [APIORCISFBSCS], [BCE], [BPP], [GEA] [62]
  IHF repressor ndhp Sigma70 26.0 -68.0 ndh
ttcattgctgTAACCTGTTGTTAAttaagagcta
1166011 1166023 [APIORCISFBSCS], [BCE], [BPP], [GEA] [62]
  IHF activator nirBp Sigma70 -115.0 -139.0 nirB, nirD, nirC, cysG
catgaaatatCAGACAATTCCGTGacttaagaaa
3493866 3493878 [APIORCISFBSCS], [BPP], [GEA] [63], [64]
  IHF repressor nirBp Sigma70 -88.0 -112.0 nirB, nirD, nirC, cysG
taagaaaattTATACAAATCAGCAatatacccat
3493893 3493905 [BCE], [BPP], [GEA] [63], [64], [65]
  IHF repressor nmpCp nd -144.0 nd nmpC
tataaattggCTAATAGATTTATTtttattcagc
577008 577020 [APIORCISFBSCS], [SM] [66]
  IHF activator norVp Sigma54 -48.0 -85.0 norV, norW
aattttatttATAGAGTAAAAACAatcagataaa
2832385 2832397 [BPP] [67]
  IHF repressor norVp Sigma54 17.0 -21.0 norV, norW
catctttttaGAACACGCTGAATAaattgaggtt
2832449 2832461 [BPP] [67]
  IHF activator nrfAp Sigma70 -127.0 -220.0 nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG
tgattaattcTTTGAGGAACATGCagttatgcat
4287538 4287550 [AIBSCS], [BPP], [GEA], [SM] [11], [68]
  IHF repressor nrfAp Sigma70 -55.0 -148.0 nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG
tggtattttaCATGCACTTACAATtgattaaaga
4287610 4287622 [BPP], [GEA] [9], [10]
  IHF repressor nuoAp2 Sigma70 -83.0 -173.0 nuoA, nuoB, nuoC, nuoE, nuoF, nuoG, nuoH, nuoI, nuoJ, nuoK, nuoL, nuoM, nuoN
actaatgtgaAGAAACTTTTGTTAaagttgacaa
2405239 2405251 [APIORCISFBSCS], [BPP], [GEA], [SM] [69], [70]
  IHF repressor nuoAp2 Sigma70 -74.0 -164.0 nuoA, nuoB, nuoC, nuoE, nuoF, nuoG, nuoH, nuoI, nuoJ, nuoK, nuoL, nuoM, nuoN
aagaaactttTGTTAAAGTTGACAaaaggttata
2405230 2405242 [APIORCISFBSCS], [BPP], [GEA] [69], [70]
  IHF repressor nuoAp2 Sigma70 -66.0 -156.0 nuoA, nuoB, nuoC, nuoE, nuoF, nuoG, nuoH, nuoI, nuoJ, nuoK, nuoL, nuoM, nuoN
tttgttaaagTTGACAAAAGGTTAtagaaaggag
2405222 2405234 [APIORCISFBSCS], [BPP], [GEA] [69], [70]
  IHF repressor ompCp1 Sigma70 -182.0 -263.0 ompC
atacttaagaATAAGTTATTGATTttaaccttga
2313006 2313018 [APIORCISFBSCS], [BCE], [BPP], [GEA]
  IHF repressor ompCp3 nd -125.0 -263.0 ompC
atacttaagaATAAGTTATTGATTttaaccttga
2313006 2313018 [APIORCISFBSCS], [BCE], [BPP], [GEA]
  IHF repressor ompFp Sigma70 -176.0 -286.0 ompF
aaatataaggAAATCATATAAATAgattaaaatt
987262 987274 [APIORCISFBSCS], [BCE]
  IHF activator ompFp Sigma70 -108.0 -218.0 ompF
acggtgttcaCAAAGTTCCTTAAAttttactttt
987194 987206 [APIORCISFBSCS], [BCE]
  IHF repressor ompFp Sigma70 -62.0 -172.0 ompF
tttctttttgAAACCAAATCTTTAtctttgtagc
987148 987160 [APIORCISFBSCS], [BCE]
  IHF repressor ompFp2 Sigma38 -176.0 -286.0 ompF
aaatataaggAAATCATATAAATAgattaaaatt
987262 987274 [APIORCISFBSCS], [BCE]
  IHF activator ompFp2 Sigma38 -108.0 -218.0 ompF
acggtgttcaCAAAGTTCCTTAAAttttactttt
987194 987206 [APIORCISFBSCS], [BCE]
  IHF repressor ompFp2 Sigma38 -62.0 -172.0 ompF
tttctttttgAAACCAAATCTTTAtctttgtagc
987148 987160 [APIORCISFBSCS], [BCE]
  IHF repressor ompRp1 Sigma70 -102.0 -225.0 ompR, envZ
caggggcgttTTCATCTCGTTGATtccctttgtc
3536803 3536815 [BPP], [SM] [71]
  IHF repressor ompRp1 Sigma70 -37.0 -160.0 ompR, envZ
gatcatatcaACAGAATCAATAATgtttcgccga
3536738 3536750 [BPP], [SM] [71]
  IHF repressor ompRp1 Sigma70 8.0 -116.0 ompR, envZ
tacttaagctGCTGTTTAATATGCtttgtaacaa
3536694 3536706 [BPP], [SM] [71]
  IHF repressor osmEp Sigma70 4.5 -23.5 osmE
ccaggcttatCTAACACGCTGATAaacaagagga
1822273 1822285 [APIORCISFBSCS], [GEA] [72]
  IHF repressor osmEp2 Sigma38 4.5 -23.5 osmE
ccaggcttatCTAACACGCTGATAaacaagagga
1822273 1822285 [APIORCISFBSCS], [GEA] [72]
  IHF repressor osmYp Sigma70 -96.5 -339.5 osmY
tcaatttcccTTCCTTATTAGCCGcttacggaat
4611050 4611062 [APIORCISFBSCS], [BPP], [GEA] [73], [74]
  IHF repressor osmYp Sigma70 -5.0 -248.0 osmY
ttgtgatctaTATTTAACAAAGTGatgacatttc
4611142 4611154 [BCE], [GEA]
  IHF repressor osmYp2 Sigma38 -96.5 -339.5 osmY
tcaatttcccTTCCTTATTAGCCGcttacggaat
4611050 4611062 [APIORCISFBSCS], [BPP], [GEA] [73], [74]
  IHF repressor osmYp2 Sigma38 -5.0 -248.0 osmY
ttgtgatctaTATTTAACAAAGTGatgacatttc
4611142 4611154 [BCE], [GEA]
  IHF activator paaAp Sigma70 -115.0 -177.0 paaA, paaB, paaC, paaD, paaE, paaF, paaG, paaH, paaI, paaJ, paaK
gcgatctgtaTAGCAACTGCGGAAaacattaatg
1453744 1453756 [APIORCISFBSCS], [BPP], [GEA], [SM] [75]
  IHF activator paaZp nd -80.0 -108.0 paaZ
cattaatgttTTCCGCAGTTGCTAtacagatcgc
1453744 1453756 [APIORCISFBSCS], [BPP], [GEA], [SM] [75]
  IHF unknown patAp Sigma38 -256.0 -292.0 patA
tttaaacacaAATCTAATTCCTTGatttaaaata
3219196 3219208 [AIBSCS] [76]
  IHF unknown patAp2 Sigma54 -256.0 -292.0 patA
tttaaacacaAATCTAATTCCTTGatttaaaata
3219196 3219208 [AIBSCS] [76]
  IHF repressor plaRp Sigma70 -4.0 -90.0 plaR
caatctgattGATGAATTTCAAAAgacataaaaa
3742616 3742628 [APIORCISFBSCS], [BPP] [77]
  IHF activator proVp3 Sigma70 -18.5 -78.5 proV, proW, proX
ttgcctcagaTTCTCAGTATGTTAGggtagaaaaa
2804730 2804744 [BPP], [GEA] [78]
  IHF activator proVp3 Sigma70 140.0 80.0 proV, proW, proX
gttcaaatatATCGAACAAGGACTTTcaaaagaaca
2804887 2804902 [BPP], [GEA] [78]
  IHF activator pspAp Sigma54 -42.5 -83.5 pspA, pspB, pspC, pspD, pspE
atcagatcttTATAAATCAAAAAGataaaaaatt
1367989 1368001 [APIORCISFBSCS], [BCE], [BPP], [GEA] [79], [80]
  IHF activator pspGp Sigma54 -38.5 -62.5 pspG
ttttgctgttAAATCAATAGATTAtttttggcat
4262771 4262783 [ICA] [81]
  IHF activator pstSp Sigma70 16.5 -27.5 pstS, pstC, pstA, pstB, phoU
cgtagccaacAAACAATGCTTTATgaatcctccc
3911546 3911558 [BPP], [GEA] [82], [83], [84]
  IHF activator pstSp2 Sigma38 16.5 -27.5 pstS, pstC, pstA, pstB, phoU
cgtagccaacAAACAATGCTTTATgaatcctccc
3911546 3911558 [BPP], [GEA] [82], [83], [84]
  IHF repressor rpoEp1b Sigma70 -59.5 -288.5 rseD, rpoE, rseA, rseB, rseC
ccgctaccgaTAATCAACACGTCacatgaatgt
2710447 2710459 [APIORCISFBSCS], [GEA], [IC] [85]
  IHF activator rpoHp6 Sigma54 -326.0 -356.0 rpoH
acgaagtttgATATCAATGGCTTAtcattcgatg
3601133 3601145 [BPP], [GEA] [86]
  IHF activator rtcBp Sigma54 -62.0 -90.0 rtcB, rtcA
ataatcttttTTAAAACAATGAATtaaaaaatta
3558163 3558175 [AIBSCS] [87]
  IHF activator rtcBp Sigma54 -52.0 -80.0 rtcB, rtcA
ttaaaacaatGAATTAAAAAATTAagctgcttat
3558153 3558165 [AIBSCS] [87]
  IHF repressor sodAp Sigma70 -68.0 -119.0 sodA
cattttcctgCAAAACCATACCCTtacgaaaagt
4100685 4100697 [APIORCISFBSCS], [BPP]
  IHF repressor sodAp Sigma70 -48.0 -99.0 sodA
cccttacgaaAAGTACGGCATTGAtaatcatttt
4100705 4100717 [APIORCISFBSCS], [BPP]
  IHF repressor sodAp Sigma70 -24.0 -75.0 sodA
taatcattttCAATATCATTTAATtaactataat
4100729 4100741 [APIORCISFBSCS], [BPP]
  IHF repressor sodAp Sigma70 -1.0 -52.0 sodA
ttaactataaTGAACCAACTGCTTacgcggcatt
4100752 4100764 [APIORCISFBSCS], [BPP]
  IHF repressor sodBp Sigma70 -61.0 -116.0 sodB
gctaaaacttTACCCTGTTGTTACggcaacaggg
1735256 1735268 [AIBSCS], [GEA] [88]
  IHF activator srap Sigma38 nd nd sra nd nd [BPP], [GEA], [IGI] [89]
  IHF activator ssuEp Sigma70 -177.0 -228.0 ssuE, ssuA, ssuD, ssuC, ssuB
tgacaaatctTTAATTTATAGATTtcatgaatat
997734 997746 [APIORCISFBSCS], [BPP], [GEA] [90]
  IHF activator ssuEp Sigma70 -134.0 -185.0 ssuE, ssuA, ssuD, ssuC, ssuB
aactgaacgaGTAATTCATTGATTcaacatctaa
997691 997703 [APIORCISFBSCS], [BPP], [GEA] [90]
  IHF repressor ssuEp Sigma70 33.0 -19.0 ssuE, ssuA, ssuD, ssuC, ssuB
taacaaaaaaAGAACAATTGGTTAtaaggagaga
997525 997537 [APIORCISFBSCS], [BPP], [GEA] [90]
  IHF repressor sucAp Sigma38 nd nd sucA, sucB, sucC, sucD nd nd [BPP], [GEA], [IGI]
  IHF activator sufAp Sigma70 -145.0 -177.0 sufA, sufB, sufC, sufD, sufS, sufE
ataataaccaTTATCTAACAATGAgatacctaat
1764557 1764569 [BPP], [SM] [91]
  IHF activator tdcAp nd -103.0 -131.0 tdcA, tdcB, tdcC, tdcD, tdcE, tdcF, tdcG
tttaacttgtTGATATTTAAAGGTatttaattgt
3267190 3267202 [APIORCISFBSCS], [BCE], [BPP], [SM]
  IHF repressor tyrPp1 Sigma70 nd nd tyrP nd nd [BPP], [GEA], [IGI] [56]
  IHF repressor ubiCp Sigma70 -12.0 -75.0 ubiC, ubiA
ttgcgtattaGATCACTTAATTTGctttacatct
4252425 4252437 [APIORCISFBSCS], [GEA] [92]
  IHF repressor ulaAp Sigma70 nd nd ulaA, ulaB, ulaC, ulaD, ulaE, ulaF nd nd [BPP], [GEA], [IGI] [93]
  IHF repressor ulaGp nd nd nd ulaG nd nd [BPP], [GEA], [IGI] [93]
  IHF activator uspAp1 Sigma70 -81.0 -209.0 uspA
ggttaaccacTATCAATATATTCAtgtcgaaaat
3639896 3639908 [APIORCISFBSCS], [GEA] [94], [95]
  IHF repressor uspBp Sigma38 -54.0 -182.0 uspB
attttcgacaTGAATATATTGATAgtggttaacc
3639896 3639908 [APIORCISFBSCS], [GEA] [94]
  IHF activator yadVp1 Sigma70 nd nd yadV, htrE nd nd [BPP], [GEA], [IGI] [96]
  IHF activator yadVp2 Sigma38 nd nd yadV, htrE nd nd [BPP], [GEA], [IGI] [96]
  IHF activator yadVp3 Sigma70 nd nd yadV, htrE nd nd [BPP], [GEA], [IGI] [96]
  IHF activator yeiLp Sigma38 -227.0 -292.0 yeiL
aatgttttatCAAGCGTCTGATTAcccgctacaa
2255057 2255069 [APIORCISFBSCS], [GEA] [97]
  IHF activator yeiLp Sigma38 -193.0 -258.0 yeiL
tagtgatgccTAATAAATCTATTGccggatgttt
2255091 2255103 [APIORCISFBSCS], [GEA] [97]
  IHF activator yiaKp Sigma70 -49.5 -108.5 yiaK, yiaL, yiaM, yiaN, yiaO, lyxK, sgbH, sgbU, sgbE
tttatgtcttTTGAAATTCATCAAtcagattgcc
3742618 3742630 [APIORCISFBSCS], [BPP], [GEA], [SM] [77]
  IHF activator yjbEp1 Sigma70 -133.0 -181.0 yjbE, yjbF, yjbG, yjbH
tgtttttattTTAAGTTTATGATTtttattgtta
4235719 4235731 [APIORCISFBSCS], [BPP] [98]