RegulonDB RegulonDB 10.9:Regulon Page

YcjW DNA-binding transcriptional dual regulator

Synonyms: YcjW
YcjW is a transcriptional regulator involved in the control of carbohydrate metabolism genes [1]. ycjW was identified in a screen for genes that reduce the lethal effects of stress. A ycjW insertion mutant is more sensitive than wild type to mitomycin C [].

Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
YcjW Functional   [HIFS], [IDA], [IMP] [1], [2], [3], [4]
Evolutionary Family: GalR/LacI
Connectivity class: Local Regulator
Gene name: ycjW
  Genome position: 1382963-1383961
  Length: 999 bp / 332 aa
Operon name: ycjW
TU(s) encoding the TF:
Transcription unit        Promoter

Regulated gene(s)
Regulated operon(s)
First gene in the operon(s)
Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)

Transcription factor regulation    

Transcription factor binding sites (TFBSs) arrangements

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence LeftPos RightPos Evidence (Confirmed, Strong, Weak) References

High-throughput Transcription factor binding sites (TFBSs)

  Functional conformation Function Object name Object type Distance to first Gene Sequence LeftPos RightPos Center Position Growth Condition Evidence (Confirmed, Strong, Weak) References
  YcjW repressor ycjMNOPQRSTUV-ymjB-ompG Transcription-Unit nd
1370190 1370203 1370196.5 nd [BPP], [GEA] [1]

Evolutionary conservation of regulatory elements    
     Note: Evolutionary conservation of regulatory interactions and promoters is limited to gammaproteobacteria.
Promoter-target gene evolutionary conservation