PunR, formerly named YdhB, regulates a gene involved in the purine transport process in the presence of adenosine . This protein belongs to the LysR family HTH type of transcriptional regulators [1, 2]. It appears to recognize and bind to a palindromic DNA binding motif of 23 bp .
The punR gene is located in the genome in an inverted position from its target gene . This arrangement in the genome appears to be conserved in other proteobacteria .
A punR knockout mutant reduces cellular growth under nitrogen-limiting conditions .
Genome-wide PunR binding sites were determined in vivo by chromatin immunoprecipitation method combined with lambda exonuclease digestion (ChIP-exo) in glucose M9 minimal medium .
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