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ArgR,NtrC regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
ArgR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Synonym(s): DNA-binding transcriptional dual regulator ArgR, XerA
Gene name(s): argR
Functional conformation(s): ArgR , ArgR-L-arginine
Coregulator(s): AdiY, ArgR, CRP, DksA-ppGpp, FNR, Fur, GadE, H-NS, HdfR, IHF, Lrp, Nac, NtrC, PhoP, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
NtrC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional dual regulator NtrC, GlnG, GlnT, NtrC response regulator
Gene name(s): glnG
Functional conformation(s): NtrC-Pasp
Coregulator(s): ArcA, ArgR, CRP, CysB, FNR, Fis, Fur, GadX, GlrR, IHF, Nac, NtrC, PhoP, RcsB, RutR, ppGpp

REGULATION EXERTED BY ArgR,NtrC Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
ArgR activator NtrC activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
ArgR-L-arginine activator astCp2 astE , astB , astD , astA , astC 1832157 1832174 -121.5 tattcacccaCATCGCAAACGTATTCACTttatatgcac [EME] [1]
[2]
ArgR-L-arginine activator astCp2 astE , astB , astD , astA , astC 1832135 1832152 -99.5 attcactttaTATGCACTTTAAATGCATAtggtttggtt   [2]
ArgR-L-arginine activator astCp2 astE , astB , astD , astA , astC 1832114 1832131 -78.5 aatgcatatgGTTTGGTTATAACTCCTTGatttccagtt   [2]
ArgR-L-arginine activator astCp2 astE , astB , astD , astA , astC 1832083 1832100 -47.5 ttccagttagCCTCCGCCGTTTATGCACTtttatcactg   [2]
NtrC-Pasp activator astCp2 astE , astB , astD , astA , astC 1832311 1832327 -275.0 ggttgttaatGATGTCAACGATGGCGCAaaaaatgccc   [2]
NtrC-Pasp activator astCp2 astE , astB , astD , astA , astC 1832289 1832305 -253.0 ggcgcaaaaaATGCCCGCTTTTGGTGCGcgctgcgtca   [2]
NtrC-Pasp activator astCp2 astE , astB , astD , astA , astC 1832269 1832285 -233.0 ttggtgcgcgCTGCGTCAGAATGGCGCAgtaatttcca   [2]

Evidence: [EME] Expression microarray evidence
Reference(s): [1] Caldara M., et al., 2006
[2] Kiupakis AK., et al., 2002



Reference(s)    

 [1] Caldara M., Charlier D., Cunin R., 2006, The arginine regulon of Escherichia coli: whole-system transcriptome analysis discovers new genes and provides an integrated view of arginine regulation., Microbiology 152(Pt 11):3343-54

 [2] Kiupakis AK., Reitzer L., 2002, ArgR-independent induction and ArgR-dependent superinduction of the astCADBE operon in Escherichia coli., J Bacteriol 184(11):2940-50


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