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FlhDC regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
FlhDC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): FlhDC DNA-binding transcriptional dual regulator
Gene name(s): flhC, flhD
Functional conformation(s): FlhDC
Coregulator(s): ArcA, BtsR, CRP, CsgD, DpiA, FNR, FhlA, Fis, FlhDC, GalR, GalS, GlpR, H-NS, IHF, MatA, ModE, NarL, NarP, NsrR, SutR
Summary: TF Summary ...[more]

REGULATION EXERTED BY FlhDC Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FlhDC activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
FlhDC activator fliLp1 fliL , fliM , fliN , fliO , fliP , fliQ , fliR 2019511 2019527 -65.0 tattttcgccTAACGTCAGAGGTAGCACcgtaatccgc   [1]
[2]
[3]
FlhDC activator fliLp1 fliL , fliM , fliN , fliO , fliP , fliQ , fliR 2019539 2019555 -37.0 cgtaatccgcGTCTTTTCCCCGCTTTGTtgcgctcaag   [1]
[2]
[4]
FlhDC activator fliDp fliD , fliS , fliT 2003740 2003756 -69.0 cattttttgtTAGTCGCCGAAATACTCTtttctctgcc   [1]
[3]
FlhDC activator fliDp fliD , fliS , fliT 2003768 2003784 -41.0 tttctctgccCCTTATTCCCGCTATTAAaaaaaacaat   [1]
[3]
FlhDC activator gltIp1 gltL , gltK , gltJ , sroC , gltI 687950 687966 -62.0 aaatggcgaaGAAACGGTCTAAATAGGCtgattcaagg   [3]
FlhDC activator gltIp1 gltL , gltK , gltJ , sroC , gltI 687935 687953 -47.5 cggtctaaatAGGCTGATTCAAGGCATTTacgggagaaa   [3]
FlhDC activator flgAp flgN , flgM , flgA 1130945 1130961 -68.0 ttacgcgcgcGTTATCGGCGGAATAAACgcaaaatggg   [3]
FlhDC activator flgAp flgN , flgM , flgA 1130917 1130933 -40.0 gcaaaatgggTCGCTATTTATGCCGTTGatggtcattg   [3]
FlhDC activator flgBp flgB , flgC , flgD , flgE , flgF , flgG , flgH , flgI , flgJ 1130943 1130959 -41.5 gacccattttGCGTTTATTCCGCCGATAacgcgcgcgt   [3]
FlhDC activator flhBp flhE , flhA , flhB 1966275 1966293 -67.5 atgtgtggcaGCAAAAGCCCTAAATCCCGcctgttttgc   [2]
[3]
FlhDC activator flhBp flhE , flhA , flhB 1966247 1966263 -39.0 cctgttttgcCCCTTACTCAAACCATTGaacgctttgc   [2]
[3]
FlhDC activator ycgRp ycgR

Reference(s): [1] Brandi A., et al., 2016
[2] Liu X., et al., 1994
[3] Stafford GP., et al., 2005
[4] Liu X., et al., 1996



Reference(s)    

 [1] Brandi A., Giangrossi M., Giuliodori AM., Falconi M., 2016, An Interplay among FIS, H-NS, and Guanosine Tetraphosphate Modulates Transcription of the Escherichia coli cspA Gene under Physiological Growth Conditions., Front Mol Biosci 3:19

 [2] Liu X., Matsumura P., 1994, The FlhD/FlhC complex, a transcriptional activator of the Escherichia coli flagellar class II operons., J Bacteriol 176(23):7345-51

 [3] Stafford GP., Ogi T., Hughes C., 2005, Binding and transcriptional activation of non-flagellar genes by the Escherichia coli flagellar master regulator FlhD2C2., Microbiology 151(Pt 6):1779-88

 [4] Liu X., Matsumura P., 1996, Differential regulation of multiple overlapping promoters in flagellar class II operons in Escherichia coli., Mol Microbiol 21(3):613-20

 [5] Ko M., Park C., 2000, Two novel flagellar components and H-NS are involved in the motor function of Escherichia coli., J Mol Biol 303(3):371-82

 [6] Park K., Choi S., Ko M., Park C., 2001, Novel sigmaF-dependent genes of Escherichia coli found using a specified promoter consensus., FEMS Microbiol Lett 202(2):243-50


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