RegulonDB RegulonDB 10.9: Regulon Form
   
   


FNR,MalT regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
FNR Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional dual regulator FNR, NirA, NirR, OssA, OxrA
Gene name(s): fnr
Functional conformation(s): FNR , FNR-[4Fe-4S]2+ reduced , FNR-[2Fe-2S]2+ oxidized
Coregulator(s): AcrR, AdiY, ArcA, ArgP, ArgR, BtsR, CRP, CadC, CaiF, Cbl, CdaR, Cra, CueR, CusR, CysB, DcuR, DksA, DksA-ppGpp, DnaA, DpiA, EvgA, ExuR, FNR, FhlA, Fis, FlhDC, Fur, GadE, GadE-RcsB, GadW, GadX, GcvA, GlpR, H-NS, HdfR, HprR, HyfR, HypT, IHF, LeuO, Lrp, MalT, MarA, MetR, MlrA, ModE, Nac, NagC, NarL, NarP, NfeR, NikR, NorR, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PhoB, PhoP, PurR, PuuR, RcsB, Rob, RstA, RutR, SlyA, SoxR, SoxS, TdcA, TdcR, TorR, YeiL, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
MalT Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional activator MalT, MalA
Gene name(s): malT
Functional conformation(s): MalT-maltotriose-ATP , MalT-maltotriose-ADP , MalT , MalT-Aes , MalT-MalK , MalT-MalY
Coregulator(s): CRP, CreB, FNR, Fis, H-NS, MalT, PhoP, StpA
Summary: TF Summary ...[more]

REGULATION EXERTED BY FNR,MalT Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FNR activator MalT activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
MalT-maltotriose-ATP activator malPp malQ , malP 3552601 3552611 -95.5 actagctttaAGTGGTTGAGAtcacatttcc    
MalT-maltotriose-ATP activator malPp malQ , malP 3552579 3552589 -73.5 cacatttcctTGCTCATCCCCgcaactcctc   [1]
MalT-maltotriose-ATP activator malPp malQ , malP 3552566 3552576 -60.5 tcatccccgcAACTCCTCCCTgcctaatccc   [1]
MalT-maltotriose-ATP activator malPp malQ , malP 3552543 3552553 -37.5 ctaatcccccGCAGGATGAGGaaggtcaaca   [1]
FNR activator malPp malQ , malP 3552631 3552644 -127.5 attgcattgaTTTGATGCTAATCCTgtggtttgca   [2]

Reference(s): [1] Danot O., et al., 1994
[2] Constantinidou C., et al., 2006



Reference(s)    

 [1] Danot O., Raibaud O., 1994, Multiple protein-DNA and protein-protein interactions are involved in transcriptional activation by MalT., Mol Microbiol 14(2):335-46

 [2] Constantinidou C., Hobman JL., Griffiths L., Patel MD., Penn CW., Cole JA., Overton TW., 2006, A reassessment of the FNR regulon and transcriptomic analysis of the effects of nitrate, nitrite, NarXL, and NarQP as Escherichia coli K12 adapts from aerobic to anaerobic growth., J Biol Chem 281(8):4802-15


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