RegulonDB RegulonDB 10.9: Regulon Form
   
   


CRP,CytR,DnaA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
CRP Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): Cap, Csm, DNA-binding transcriptional dual regulator CRP, GurB
Gene name(s): crp
Functional conformation(s): CRP-cAMP , CRP
Coregulator(s): AcrR, AdiY, AgaR, AraC, ArcA, ArgP, ArgR, AscG, BasR, BolA, BtsR, CRP, CRP-Sxy, CaiF, ChbR, ComR, CpxR, Cra, CreB, CsgD, CspA, CsqR, CusR, CytR, DcuR, DeoR, DgoR, DksA-ppGpp, DnaA, DpiA, DsdC, EbgR, EnvY, EvgA, ExuR, FNR, FadR, FeaR, FhlA, Fis, FlhDC, FliZ, FucR, Fur, GadE, GadE-RcsB, GadW, GadX, GalR, GalS, GatR, GcvA, GlaR, GlcC, GlpR, GlrR, GntR, GutM, H-NS, HU, HdfR, HipB, HprR, HyfR, HypT, IHF, IclR, IdnR, LacI, LeuO, LexA, LrhA, Lrp, LsrR, MalI, MalT, MarA, MarR, MatA, McbR, MelR, MetJ, MhpR, Mlc, MlrA, ModE, MprA, MqsA, MurR, Nac, NadR, NagC, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PhoB, PhoP, PrpR, PurR, PuuR, QseB, RbsR, RcdA, RcsAB, RcsB, RcsB-BglJ, RhaR, RhaS, Rob, RstA, SdiA, SlyA, SoxR, SoxS, SrlR, StpA, TdcA, TdcR, TorR, TreR, UhpA, UidR, UlaR, UvrY, UxuR, XylR, YdeO, YiaJ, YjjQ, ZraR, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
DnaA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): chromosomal replication initiator protein DnaA, chromosomal replication initiator protein/DNA-binding transcriptional dual regulator DnaA
Gene name(s): dnaA
Functional conformation(s): DnaA-ATP , DnaA
Coregulator(s): ArcA, ArgP, CRP, CytR, DnaA, FNR, Fis, H-NS, LexA, MarA, NrdR, PurR, Rob, SoxS, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
CytR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Synonym(s): DNA-binding transcriptional repressor CytR
Gene name(s): cytR
Functional conformation(s): CytR , CytR-cytidine
Coregulator(s): CRP, CytR, DeoR, DnaA, Fis, ModE, Nac, NsrR
Summary: TF Summary ...[more]

REGULATION EXERTED BY CRP,CytR,DnaA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CRP repressor CytR repressor DnaA repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
DnaA-ATP repressor rpoHp4 rpoH 3600890 3600898 -31.0 tgcattgaacTTGTGGATAAaatcacggtc    
DnaA-ATP repressor rpoHp4 rpoH 3600914 3600922 -55.0 ttgtgcgtaaTTTATTCACAagcttgcatt    
CRP-cAMP repressor rpoHp4 rpoH 3600880 3600901 -27.5 gcttgcattgAACTTGTGGATAAAATCACGGTCtgataaaaca    
CRP-cAMP repressor rpoHp4 rpoH 3600933 3600954 -80.5 ctcttcccggTATTTCATCTCTATGTCACATTTtgtgcgtaat    
DnaA-ATP repressor rpoHp3 rpoH 3600914 3600922 -48.0 ttgtgcgtaaTTTATTCACAagcttgcatt    
CRP-cAMP repressor rpoHp3 rpoH 3600880 3600901 -20.5 gcttgcattgAACTTGTGGATAAAATCACGGTCtgataaaaca    
CRP-cAMP repressor rpoHp3 rpoH 3600933 3600954 -73.5 ctcttcccggTATTTCATCTCTATGTCACATTTtgtgcgtaat    
CytR repressor rpoHp4 rpoH 3600896 3600912 -40.5 ttattcacaaGCTTGCATTGAACTTGTggataaaatc    
CytR repressor rpoHp3 rpoH 3600896 3600912 -33.5 ttattcacaaGCTTGCATTGAACTTGTggataaaatc    
CytR repressor rpoHp3 rpoH 3600913 3600932 -52.0 tgtcacatttTGTGCGTAATTTATTCACAAgcttgcattg   [1]
CytR repressor rpoHp4 rpoH 3600913 3600932 -59.0 tgtcacatttTGTGCGTAATTTATTCACAAgcttgcattg   [1]

Reference(s): [1] Kallipolitis BH., et al., 1998



Reference(s)    

 [1] Kallipolitis BH., Valentin-Hansen P., 1998, Transcription of rpoH, encoding the Escherichia coli heat-shock regulator sigma32, is negatively controlled by the cAMP-CRP/CytR nucleoprotein complex., Mol Microbiol 29(4):1091-9


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