RegulonDB RegulonDB 10.9: Regulon Form
   
   


GadX regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
GadX Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator GadX, YhiX
Gene name(s): gadX
Functional conformation(s): GadX
Coregulator(s): AdiY, AraC, ArcA, CRP, CadC, CspA, EvgA, FNR, Fis, FliZ, Fur, GadE, GadE-RcsB, GadW, GadX, H-NS, Lrp, MarA, MqsA, NagC, NtrC, OmpR, PhoB, PhoP, RcsB, RutR, SdiA, TorR, YdeO, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY GadX Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
GadX repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
GadX repressor btuBp btuB , murI 4163463 4163482 74.5 cggtaaggaaAGGTGCGATGATTGCGTTATGcggacactgc   [1]
GadX repressor btuBp btuB , murI 4163494 4163513 105.5 cggacactgcCATTCGGTGGGAAGTCATCATctcttagtat   [1]
GadX repressor btuBp btuB , murI 4163523 4163542 134.5 atctcttagtATCTTAGATACCCCTCCAAGCccgaagacct   [1]
GadX repressor ynfBp ynfB , speG 1655605 1655624 -94.5 ttaaccacaaCCAGGGCAGAAAGCATCCAATaatttcacac   [2]
GadX activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
GadX activator asnBp asnB

Reference(s): [1] Lei GS., et al., 2011
[2] Seo SW., et al., 2015



Reference(s)    

 [1] Lei GS., Syu WJ., Liang PH., Chak KF., Hu WS., Hu ST., 2011, Repression of btuB gene transcription in Escherichia coli by the GadX protein., BMC Microbiol 11(1):33

 [2] Seo SW., Kim D., O'Brien EJ., Szubin R., Palsson BO., 2015, Decoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli., Nat Commun 6:7970

 [3] Hommais F., Krin E., Coppee JY., Lacroix C., Yeramian E., Danchin A., Bertin P., 2004, GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli., Microbiology 150(Pt 1):61-72


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