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CpxR,TyrR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
TyrR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Synonym(s): DNA-binding transcriptional dual regulator TyrR
Gene name(s): tyrR
Functional conformation(s): TyrR-tyrosine , TyrR , TyrR-phenylalanine , TyrR-L-tryptophan
Coregulator(s): CpxR, Cra, HU, IHF, PgrR, SoxR, TrpR, TyrR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
CpxR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): CpxR response regulator, DNA-binding transcriptional dual regulator CpxR, YiiA
Gene name(s): cpxR
Functional conformation(s): CpxR-Phosphorylated , CpxR
Coregulator(s): AcrR, BaeR, BasR, BolA, BtsR, CRP, CpxR, Cra, CsgD, CysB, EnvY, Fis, FliZ, Fur, GadE, H-NS, IHF, Lrp, MarA, MarR, MlrA, MqsA, NsrR, OmpR, PdhR, PhoB, RcdA, RcsAB, RcsB, Rob, RstA, SoxS, TyrR, YjjQ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY CpxR,TyrR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CpxR activator TyrR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
CpxR-Phosphorylated activator aroGp aroG 785546 785560 -38.0 cgttcatagtGTAAAACCCCGTTTACacattctgac   [1]
TyrR-phenylalanine repressor aroGp aroG 785544 785561 -38.0 tccgttcataGTGTAAAACCCCGTTTACAcattctgacg   [2]

Reference(s): [1] Yamamoto K., et al., 2006
[2] Baseggio N., et al., 1990



Reference(s)    

 [1] Yamamoto K., Ishihama A., 2006, Characterization of copper-inducible promoters regulated by CpxA/CpxR in Escherichia coli., Biosci Biotechnol Biochem 70(7):1688-95

 [2] Baseggio N., Davies WD., Davidson BE., 1990, Identification of the promoter, operator, and 5' and 3' ends of the mRNA of the Escherichia coli K-12 gene aroG., J Bacteriol 172(5):2547-57


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