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PhoP,SlyA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
PhoP Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional dual regulator PhoP, PhoP response regulator
Gene name(s): phoP
Functional conformation(s): PhoP-Phosphorylated , PhoP
Coregulator(s): AcrR, ArcA, ArgR, BasR, CRP, CysB, EnvR, EvgA, FNR, FadR, FliZ, GadE, GadW, GadX, H-NS, HypT, Lrp, MalT, MarA, MetJ, MprA, NagC, NarL, NarP, NtrC, OmpR, PdhR, PhoP, PurR, RbsR, RcsB, Rob, RutR, SdiA, SlyA, SoxR, SoxS, TorR, UvrY, YdeO, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
SlyA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Gene name(s): slyA
Functional conformation(s): SlyA
Coregulator(s): ArcA, CRP, DksA-ppGpp, FNR, Fis, Fur, H-NS, IHF, LeuO, LrhA, McbR, PaaX, PhoP, RcdA, SdiA, SlyA, StpA, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY PhoP,SlyA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
PhoP activator SlyA activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
PhoP-Phosphorylated activator pagPp pagP 656486 656502 -32.0 atgttgggtcTATTAAGGTTATGTTAATtgtagctttg   [1]
SlyA activator pagPp pagP 656417 656416 -109.5 aatcgatgcgCggaaatattt   [2]
SlyA activator pagPp pagP 656510 656523 -10.0 taattgtagcTTTGCTATGCTAGTagtagatttt   [2]
SlyA activator pagPp pagP 656431 656444 -89.0 aatatttaacTTGAACAAGCGGAAataaatagag   [2]

Reference(s): [1] Eguchi Y., et al., 2004
[2] Klitgaard RN., et al., 2018



Reference(s)    

 [1] Eguchi Y., Okada T., Minagawa S., Oshima T., Mori H., Yamamoto K., Ishihama A., Utsumi R., 2004, Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli., J Bacteriol 186(10):3006-14

 [2] Klitgaard RN., Jana B., Guardabassi L., Nielsen KL., Lobner-Olesen A., 2018, DNA Damage Repair and Drug Efflux as Potential Targets for Reversing Low or Intermediate Ciprofloxacin Resistance in E. coli K-12., Front Microbiol 9:1438


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