RegulonDB RegulonDB 10.9: Regulon Form
   
   


EvgA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
EvgA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional activator EvgA, EvgA response regulator
Gene name(s): evgA
Functional conformation(s): EvgA-phosphorylated , EvgA
Coregulator(s): CRP, EvgA, FNR, FliZ, GadE, GadW, GadX, H-NS, NagC, NarL, NarP, PhoP, RcsB, UvrY, YdeO
Summary: TF Summary ...[more]

REGULATION EXERTED BY EvgA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
EvgA activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
EvgA-phosphorylated activator frcp frc 2493506 2493523 -75.5 atcaccggcgCTTCTTACAGTTGTAAGAAtaacatcaca   [1]
[2]
EvgA-phosphorylated activator yfdXp yfdE , yfdV , oxc , frc , yfdX 2494538 2494555 -113.5 caggaagcatATTCCTACAATTGTAAGACtaaaatactt   [1]
[2]
EvgA-phosphorylated activator yegRp yegZ , yegR 2168413 2168430 -72.5 aatgtccgtaATTCCTACTTATGTAGGAAatgttgtaca   [1]
[2]
EvgA-phosphorylated activator yfdXp yfdE , yfdV , oxc , frc , yfdX 2494500 2494517 -75.5 tcttgcgataATAACTACAACTGTAAGATaaccctttca   [1]
EvgA-phosphorylated activator acrDp acrD 2587435 2587453 -31.5 aatgtaatgcCTCCTACTGACCAAAGAATacttgcactt   [3]

Reference(s): [1] Itou J., et al., 2009
[2] Masuda N., et al., 2003
[3] Hirakawa H., et al., 2003



Reference(s)    

 [1] Itou J., Eguchi Y., Utsumi R., 2009, Molecular mechanism of transcriptional cascade initiated by the EvgS/EvgA system in Escherichia coli K-12., Biosci Biotechnol Biochem 73(4):870-8

 [2] Masuda N., Church GM., 2003, Regulatory network of acid resistance genes in Escherichia coli., Mol Microbiol 48(3):699-712

 [3] Hirakawa H., Nishino K., Yamada J., Hirata T., Yamaguchi A., 2003, Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli., J Antimicrob Chemother 52(4):576-82


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