RegulonDB

TRANSCRIPTION FACTOR:

Name:

SoxS	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional dual regulator SoxS, regulation of superoxide response regulon

Gene name(s):

soxS

Functional conformation(s):

SoxS

Coregulator(s):

AcrR, ArcA, BasR, CRP, CpxR, Cra, DnaA, EnvR, FNR, Fis, Fur, H-NS, HU, IHF, Lrp, MarA, MarR, Mlc, MprA, NarL, OmpR, OxyR, PhoP, Rob, SoxR, SoxS, Zur

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Name:

OxyR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional dual regulator OxyR, MomR, Mor, bifunctional regulatory protein sensor for oxidative stress

Gene name(s):

oxyR

Functional conformation(s):

OxyR

Coregulator(s):

CRP, DksA, ExuR, FNR, Fis, Fur, H-NS, IHF, IscR, MarA, MetJ, MetR, MntR, NarL, NarP, NsrR, OxyR, Rob, SoxS, UxuR, YdcI, Zur, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY OxyR,SoxS

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
OxyR activator SoxS activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
SoxS	activator	uofp	fur , uof	710881	710900	-61.5	tacgccgtatTAATAGATAATGCCAATCAAaataattgct	[RSE]	[1] [2]
OxyR	activator	uofp	fur , uof	710883	710899	-62.0	acgccgtattAATAGATAATGCCAATCaaaataattg	[GEA] [RSE]	[1] [2]
OxyR	activator	uofp	fur , uof	710861	710877	-40.0	caatcaaaatAATTGCTACAAATTTGTaacttttgct	[GEA]	[2]

Evidence:	[RSE] RNA-seq evidence [GEA] Gene expression analysis
Reference(s):	[1] Seo SW., et al., 2015 [2] Zheng M., et al., 1999

Reference(s)
[1] Seo SW., Kim D., Szubin R., Palsson BO., 2015, Genome-wide Reconstruction of OxyR and SoxRS Transcriptional Regulatory Networks under Oxidative Stress in Escherichia coli K-12 MG1655., Cell Rep 12(8):1289-99
[2] Zheng M., Doan B., Schneider TD., Storz G., 1999, OxyR and SoxRS regulation of fur., J Bacteriol 181(15):4639-43