RegulonDB

TRANSCRIPTION FACTOR:

Name:

Fis	Weight Matrix Tractordb tool

Connectivity class

Global Regulator

Sensing Class

TFs for DNA-bending

Synonym(s):

DNA-binding transcriptional dual regulator Fis, Nbp, site-specific DNA inversion stimulation factor

Gene name(s):

fis

Functional conformation(s):

Fis

Coregulator(s):

AcrR, AdiY, AppY, ArcA, ArgP, BasR, CRP, CpxR, Cra, CreB, CspA, CusR, CytR, DeoR, DksA, DksA-ppGpp, DnaA, FNR, FadR, Fis, FlhDC, FliZ, Fur, GadE, GadE-RcsB, GadW, GadX, GlcC, GlpR, H-NS, HprR, IHF, IscR, LeuO, Lrp, MalT, MarA, MarR, MazE, MazE-MazF, Mlc, MntR, ModE, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PepA, PurR, RcsB, RcsB-BglJ, Rob, RstA, RutR, SlyA, SoxS, StpA, TorR, XylR, YdeO, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

MazE	Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

ChpAI, ChpR, antitoxin of the MazF-MazE toxin-antitoxin system MazE

Gene name(s):

mazE

Functional conformation(s):

MazE

Coregulator(s):

Fis, MazE, MazE-MazF, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

MazE-MazF

Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

MazE-MazF "addiction module", MazEF, MazFE

Gene name(s):

mazE, mazF

Functional conformation(s):

MazE-MazF

Coregulator(s):

Fis, MazE, MazE-MazF, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY Fis,MazE,MazE-MazF,ppGpp

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
Fis activator MazE repressor MazE-MazF repressor ppGpp inhibition
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
Fis	activator	mazEp1	mazG , mazF , mazE	2911401	2911415	-40.5	gggagttaggCCGAAATTTGCTCGTatctacaatg	[GEA]	[1]
MazE	repressor	mazEp1	mazG , mazF , mazE	2911363	2911388	-7.0	ctacaatgtaGATTGATATATACTGTATCTACATATgatagcggtt	[BCE] [GEA] [SM]	[1]
MazE	repressor	mazEp1	mazG , mazF , mazE	2911376	2911403	-21.0	gaaatttgctCGTATCTACAATGTAGATTGATATATACtgtatctaca	[BCE] [GEA] [SM]	[1]
MazE-MazF	repressor	mazEp1	mazG , mazF , mazE	2911362	2911389	-7.0	tctacaatgtAGATTGATATATACTGTATCTACATATGatagcggttt	[BCE] [GEA] [SM]	[1]
MazE-MazF	repressor	mazEp1	mazG , mazF , mazE	2911376	2911403	-21.0	gaaatttgctCGTATCTACAATGTAGATTGATATATACtgtatctaca	[BCE] [GEA] [SM]	[1]

Evidence:	[GEA] Gene expression analysis [BCE] Binding of cellular extracts [SM] Site mutation
Reference(s):	[1] Marianovsky I., et al., 2001