RegulonDB RegulonDB 11.0: Regulon Form
   
   


CueR,FNR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
FNR Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional dual regulator FNR, NirA, NirR, OssA, OxrA
Gene name(s): fnr
Functional conformation(s): FNR , FNR-[4Fe-4S]2+ reduced , FNR-[2Fe-2S]2+ oxidized
Coregulator(s): AcrR, AdiY, ArcA, ArgP, ArgR, BtsR, CRP, CadC, CaiF, Cbl, CdaR, Cra, CueR, CusR, CysB, DcuR, DksA, DksA-ppGpp, DnaA, DpiA, EvgA, ExuR, FNR, FhlA, Fis, FlhDC, Fur, GadE, GadE-RcsB, GadW, GadX, GcvA, GlpR, H-NS, HdfR, HprR, HyfR, HypT, IHF, LeuO, Lrp, MalT, MarA, MetR, MlrA, ModE, Nac, NagC, NarL, NarP, NfeR, NikR, NorR, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PhoB, PhoP, PurR, PuuR, RcsB, Rob, RstA, RutR, SlyA, SoxR, SoxS, TdcA, TdcR, TorR, YeiL, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
CueR      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): CopR, DNA-binding transcriptional dual regulator CueR, YbbI
Gene name(s): cueR
Functional conformation(s): CueR-Cu+ , CueR-Ag , CueR-Au
Coregulator(s): CueR, FNR
Summary: TF Summary ...[more]

REGULATION EXERTED BY CueR,FNR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CueR repressor FNR activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
FNR activator moaAp1 moaA , moaB , moaC , moaD , moaE 816781 816794 -39.5 tgcctccctgATGATGTATATCAAagtaaaaccg [GEA] [1]
[2]
CueR-Cu+ repressor moaAp1 moaA , moaB , moaC , moaD , moaE 817019 817037 202.0 aaatgacttcGCCTCCCGTATCTGGAAAGgtgtacatgg [GEA] [3]

Evidence: [GEA] Gene expression analysis
Reference(s): [1] Anderson LA., et al., 2000
[2] Zupok A., et al., 2019
[3] Yamamoto K., et al., 2005



Reference(s)    

 [1] Anderson LA., McNairn E., Lubke T., Pau RN., Boxer DH., Leubke T., 2000, ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli., J Bacteriol 182(24):7035-43

 [2] Zupok A., Gorka M., Siemiatkowska B., Skirycz A., Leimkuhler S., 2019, Iron-Dependent Regulation of Molybdenum Cofactor Biosynthesis Genes in Escherichia coli., J Bacteriol 201(17)

 [3] Yamamoto K., Ishihama A., 2005, Transcriptional response of Escherichia coli to external copper., Mol Microbiol 56(1):215-27


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