RegulonDB RegulonDB 11.0: Regulon Form
   
   


AsnC,Nac regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
Nac Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator Nac
Gene name(s): nac
Functional conformation(s): Nac
Coregulator(s): AdiY, ArgP, ArgR, AsnC, CRP, CytR, FNR, Fur, GadE, HdfR, IHF, Lrp, Nac, NsrR, NtrC, PhoB, PurR, QseB
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
AsnC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Synonym(s): DNA-binding transcriptional dual regulator AsnC
Gene name(s): asnC
Functional conformation(s): AsnC , AsnC-L-asparagine
Coregulator(s): AsnC, Nac
Summary: TF Summary ...[more]

REGULATION EXERTED BY AsnC,Nac Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
AsnC repressor Nac repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
Nac repressor asnCp mnmG , mioC , asnC 3927009 3927023 16.0 atgaatcatcAATCCGCATAAGAAAatcctatgga [GEA]
[RSE]
[1]
[2]
Nac repressor asnCp mnmG , mioC , asnC 3927088 3927102 -64.0 aaaccgacacACATGCAATAATCATtcaataaaaa [GEA] [2]
Nac repressor asnCp mnmG , mioC , asnC 3927031 3927045 -7.0 taaaaaagaaGGCTAAAATAGAATGaatcatcaat [GEA] [2]
AsnC repressor asnCp mnmG , mioC , asnC 3927110 3927123 -85.5 ttgcttatgaTTAAGCAACAAAAAccgacacaca [GEA] [3]
AsnC repressor asnCp mnmG , mioC , asnC 3927079 3927092 -54.5 acatgcaataATCATTCAATAAAAagcctaactc [GEA] [3]
AsnC repressor asnCp mnmG , mioC , asnC 3927047 3927060 -22.5 tcacttttgaTTCATTAAAAAAGAaggctaaaat [GEA] [3]
AsnC repressor asnCp mnmG , mioC , asnC 3927013 3927026 12.5 agaatgaatcATCAATCCGCATAAgaaaatccta [GEA] [3]

Evidence: [GEA] Gene expression analysis
[RSE] RNA-seq evidence
Reference(s): [1] Aquino P., et al., 2017
[2] Poggio S., et al., 2002
[3] Kolling R., et al., 1985



Reference(s)    

 [1] Aquino P., Honda B., Jaini S., Lyubetskaya A., Hosur K., Chiu JG., Ekladious I., Hu D., Jin L., Sayeg MK., Stettner AI., Wang J., Wong BG., Wong WS., Alexander SL., Ba C., Bensussen SI., Bernstein DB., Braff D., Cha S., Cheng DI., Cho JH., Chou K., Chuang J., Gastler DE., Grasso DJ., Greifenberger JS., Guo C., Hawes AK., Israni DV., Jain SR., Kim J., Lei J., Li H., Li D., Li Q., Mancuso CP., Mao N., Masud SF., Meisel CL., Mi J., Nykyforchyn CS., Park M., Peterson HM., Ramirez AK., Reynolds DS., Rim NG., Saffie JC., Su H., Su WR., Su Y., Sun M., Thommes MM., Tu T., Varongchayakul N., Wagner TE., Weinberg BH., Yang R., Yaroslavsky A., Yoon C., Zhao Y., Zollinger AJ., Stringer AM., Foster JW., Wade J., Raman S., Broude N., Wong WW., Galagan JE., 2017, Coordinated regulation of acid resistance in Escherichia coli., BMC Syst Biol 11(1):1

 [2] Poggio S., Domeinzain C., Osorio A., Camarena L., 2002, The nitrogen assimilation control (Nac) protein represses asnC and asnA transcription in Escherichia coli., FEMS Microbiol Lett 206(2):151-6

 [3] Kolling R., Lother H., 1985, AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli., J Bacteriol 164(1):310-5


RegulonDB