RegulonDB

TRANSCRIPTION FACTOR:

Name:

ArgP	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional dual regulator ArgP, IciA

Gene name(s):

argP

Functional conformation(s):

ArgP-L-arginine , ArgP-L-lysine , ArgP

Coregulator(s):

ArgP, CRP, DnaA, FNR, Fis, Fur, H-NS, Lrp, LysR, Nac, NrdR, PhoB, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Name:

PhoB	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional dual regulator PhoB, PhoB response regulator, PhoT

Gene name(s):

phoB

Functional conformation(s):

PhoB , PhoB-phosphorylated

Coregulator(s):

AlpA, ArgP, AscG, CRP, CpxR, CusR, EnvY, FNR, Fur, GadE, GadE-RcsB, GadW, GadX, H-NS, HprR, IHF, Nac, NsrR, OmpR, PhoB, PrpR, QseB, RcdA, RstA, RutR

Summary:

TF Summary ...[more]

REGULATION EXERTED BY ArgP,PhoB

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
ArgP repressor PhoB activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
PhoB-phosphorylated	activator	argPp	argP	3059694	3059712	-27.0	tatatgcaacCTGACACAAAATTGTGTCAtagtgcagga	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
ArgP-L-arginine	repressor	argPp	argP	3059704	3059723	-16.5	ctgacacaaaATTGTGTCATAGTGCAGGAAaaagcattta	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] [IC]	[2]
ArgP-L-arginine	repressor	argPp	argP	3059684	3059704	-36.5	acggcttcggTATATGCAACCTGACACAAAAttgtgtcata	[IC]	[2]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis [IC] Inferred by curator
Reference(s):	[1] Han JS., et al., 1999 [2] Celis RT. 1999

Reference(s)
[1] Han JS., Park JY., Lee YS., Thony B., Hwang DS., 1999, PhoB-dependent transcriptional activation of the iciA gene during starvation for phosphate in Escherichia coli., Mol Gen Genet 262(3):448-52
[2] Celis RT., 1999, Repression and activation of arginine transport genes in Escherichia coli K 12 by the ArgP protein., J Mol Biol 294(5):1087-95