RegulonDB

TRANSCRIPTION FACTOR:

Name:

H-NS	Tractordb tool

Connectivity class

Global Regulator

Sensing Class

TFs for DNA-bending

Synonym(s):

BglY, Cur, DNA-binding protein HLP-II (HU, BH2, HD, NS), DNA-binding transcriptional dual regulator H-NS, Drc, DrdX, Drs, FimG, Hns, HnsA, Irk, MsyA, OsmZ, PilG, TopS, TopX, VirR

Gene name(s):

hns

Functional conformation(s):

H-NS

Coregulator(s):

AcrR, AdiY, ArcA, ArgP, ArgR, BasR, BolA, BtsR, CRP, CadC, CaiF, CdaR, CpxR, Cra, CreB, CsgD, CspA, CysB, DksA, DksA-ppGpp, DnaA, DpiA, EvgA, FNR, Fis, FlhDC, FliZ, Fur, GadE, GadE-RcsB, GadW, GadX, GalR, GalS, GlaR, GutM, H-NS, HU, HdfR, HypT, IHF, LacI, LeuO, LrhA, Lrp, MalT, MarA, MatA, McbR, MlrA, MntR, MqsA, NagC, NanR, NarL, NarP, NhaR, NrdR, NsrR, OmpR, OxyR, PhoB, PhoP, QseB, RcdA, RcsAB, RcsB, RcsB-BglJ, Rob, RstA, RutR, SdiA, SlyA, SoxS, SrlR, StpA, SutR, TorR, UvrY, YdeO, YjjQ, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

PhoB	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional dual regulator PhoB, PhoB response regulator, PhoT

Gene name(s):

phoB

Functional conformation(s):

PhoB , PhoB-phosphorylated

Coregulator(s):

AlpA, ArgP, AscG, CRP, CpxR, CusR, EnvY, FNR, Fur, GadE, GadE-RcsB, GadW, GadX, H-NS, HprR, IHF, Nac, NsrR, OmpR, PhoB, PrpR, QseB, RcdA, RstA, RutR

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

RstA	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional regulator RstA, RstA response regulator, UrpT

Gene name(s):

rstA

Functional conformation(s):

RstA , RstA-phosphorylated

Coregulator(s):

BasR, BolA, BtsR, CRP, CpxR, Cra, CsgD, EnvY, FNR, Fis, FliZ, Fur, H-NS, IHF, MlrA, MqsA, NarL, OmpR, PhoB, RcdA, RcsAB, RstA, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

RcdA	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

YbjK

Gene name(s):

rcdA

Functional conformation(s):

RcdA , RcdA-trimethylamine N-oxide , RcdA-tris

Coregulator(s):

ArcA, BasR, BolA, BtsR, CRP, CpxR, Cra, CsgD, FliZ, H-NS, IHF, LexA, McbR, MlrA, MqsA, OmpR, PhoB, RcdA, RcsAB, RstA, SdiA, SlyA, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY H-NS,PhoB,RcdA,RstA

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
H-NS repressor PhoB activator RcdA activator RstA activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
PhoB-phosphorylated	activator	asrp	asr	1671288	1671306	-30.0	aaaccaaccaCTCACGGAAGTCTGCCATTcccagggata	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
RstA-phosphorylated	activator	asrp	asr	1671257	1671273	-62.0	attcagcgttTGTACATATCGTTACACgctgaaacca	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[2]
H-NS	repressor	asrp	asr

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Suziedeliene E., et al., 1999 [2] Ogasawara H., et al., 2007

Reference(s)
[1] Suziedeliene E., Suziedelis K., Garbenciute V., Normark S., 1999, The acid-inducible asr gene in Escherichia coli: transcriptional control by the phoBR operon., J Bacteriol 181(7):2084-93
[2] Ogasawara H., Hasegawa A., Kanda E., Miki T., Yamamoto K., Ishihama A., 2007, Genomic SELEX search for target promoters under the control of the PhoQP-RstBA signal relay cascade., J Bacteriol 189(13):4791-9
[3] Seputiene V., Suziedelis K., Normark S., Melefors O., Suziedeliene E., 2004, Transcriptional analysis of the acid-inducible asr gene in enterobacteria., Res Microbiol 155(7):535-42
[4] Shimada T., Katayama Y., Kawakita S., Ogasawara H., Nakano M., Yamamoto K., Ishihama A., 2012, A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli., Microbiologyopen 1(4):381-94