RegulonDB RegulonDB 11.1: Regulon Form
   
   


IHF,Lrp regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
Lrp Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Sensing external and internal signals
Synonym(s): AlsB, DNA-binding transcriptional dual regulator Lrp, Ihb, LivR, Lrs, Lss, LstR, Mbf, OppI, RblA
Gene name(s): lrp
Functional conformation(s): Lrp , Lrp-L-leucine
Coregulator(s): AcrR, Ada, AdiY, AidB, ArcA, ArgP, ArgR, CRP, CadC, CpxR, Cra, DksA, DksA-ppGpp, EnvY, FNR, Fis, FliZ, Fur, GadE, GadE-RcsB, GadW, GadX, GcvA, GlaR, H-NS, HU, HdfR, IHF, LrhA, Lrp, MarA, Mlc, ModE, Nac, NarL, NhaR, NsrR, OmpR, PhoP, PurR, QseB, RcsB, Rob, SoxS, StpA, TorR, YeiL, YjjQ, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
IHF Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class TFs for DNA-bending
Synonym(s): DNA-binding transcriptional dual regulator IHF
Gene name(s): ihfB, ihfA
Functional conformation(s): IHF
Coregulator(s): AcrR, AdiY, ArcA, ArgR, AtoC, BasR, BolA, BtsR, CRP, Cbl, CpxR, Cra, CsgD, CysB, DksA, DksA-ppGpp, EnvY, FNR, FadR, FhlA, Fis, FlhDC, FliZ, Fur, GadE, GlcC, GlpR, GlrR, H-NS, HU, HdfR, HipAB, HipB, IHF, IclR, IscR, LrhA, Lrp, MarA, MatA, MlrA, MntR, ModE, MprA, MqsA, Nac, NagC, NanR, NarL, NarP, NorR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PepA, PhoB, PlaR, PspF, PurR, QseB, RcdA, RcsAB, Rob, RstA, RtcR, RutR, SlyA, SoxR, SoxS, SutR, TdcA, TdcR, TrpR, TyrR, UlaR, UvrY, YeiL, YjjQ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY IHF,Lrp Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
IHF repressor Lrp repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
Lrp repressor ompCp3 ompC 2313199 2313213 -319.0 gtttttctgtGGTAGCACAGAATAAtgaaaagtgt [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2313163 2313177 -283.5 taaagaagggTAAAAAAAACCGAATgcgaggcatc [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2313134 2313148 -254.5 ggcatccggtTGAAATAGGGGTAAAcagacattca [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2313103 2313117 -223.5 ttcagaaatgAATGACGGTAATAAAtaaagttaat [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2313031 2313045 -151.0 tttgttttgaCATTCAGTGCTGTCAaatacttaag [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2312853 2312867 28.0 gtatcatattCGTGTTGGATTATTCtgcatttttg [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
[3]
Lrp repressor ompCp3 ompC 2312822 2312836 59.0 tttggggagaATGGACTTGCCGACTgattaatgag [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Lrp repressor ompCp3 ompC 2312738 2312752 143.0 gagggttaatAACATGAAAGTTAAAgtactgtccc [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
IHF repressor ompCp3 ompC 2313006 2313018 -125.0 tacttaagaaTAAGTTATTGATTttaaccttga [EXP-IEP-GENE-EXPRESSION-ANALYSIS]  
Lrp repressor ompCp3 ompC 2312759 2312773 121.5 agcaaataaaGGCATATAACAGAGGgttaataaca [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Ernsting BR., et al., 1992
[2] Ferrario M., et al., 1995
[3] Fraenkel YM., et al., 1995



Reference(s)    

 [1] Ernsting BR., Atkinson MR., Ninfa AJ., Matthews RG., 1992, Characterization of the regulon controlled by the leucine-responsive regulatory protein in Escherichia coli., J Bacteriol 174(4):1109-18

 [2] Ferrario M., Ernsting BR., Borst DW., Wiese DE., Blumenthal RM., Matthews RG., 1995, The leucine-responsive regulatory protein of Escherichia coli negatively regulates transcription of ompC and micF and positively regulates translation of ompF., J Bacteriol 177(1):103-13

 [3] Fraenkel YM., Mandel Y., Friedberg D., Margalit H., 1995, Identification of common motifs in unaligned DNA sequences: application to Escherichia coli Lrp regulon., Comput Appl Biosci 11(4):379-87

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