RegulonDB RegulonDB 11.1: Regulon Form
   
   


FlhDC,ModE,NarL,NarP regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
ModE Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): ChlD, DNA-binding transcriptional dual regulator ModE, ModE-MoO42-, ModR
Gene name(s): modE
Functional conformation(s): ModE , ModE-molybdate
Coregulator(s): ArcA, CRP, CytR, DeoR, FNR, FhlA, Fis, FlhDC, Fur, IHF, Lrp, ModE, NarL, NarP, NsrR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
NarL Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional dual regulator NarL, FrdR, NarR, nitrate/nitrite response regulator NarL
Gene name(s): narL
Functional conformation(s): NarL , NarL-phosphorylated
Coregulator(s): AppY, ArcA, CRP, Cra, DcuR, DpiA, EvgA, FNR, FhlA, Fis, FlhDC, Fur, H-NS, IHF, IscR, Lrp, ModE, NagC, NarL, NarP, NikR, NorR, NsrR, OxyR, PhoP, RcsB, RstA, SoxS, TorR, UvrY, YdeO
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
NarP Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional dual regulator NarP, nitrate/nitrite response regulator NarP
Gene name(s): narP
Functional conformation(s): NarP , NarP-phosphorylated
Coregulator(s): AppY, ArcA, CRP, Cra, EvgA, FNR, FhlA, Fis, FlhDC, H-NS, IHF, IscR, ModE, NagC, NarL, NarP, NorR, NsrR, OxyR, PhoP, RcsB, UvrY, YdeO
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
FlhDC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): FlhDC DNA-binding transcriptional dual regulator
Gene name(s): flhC, flhD
Functional conformation(s): FlhDC
Coregulator(s): ArcA, BtsR, CRP, CsgD, DpiA, FNR, FhlA, Fis, FlhDC, GalR, GalS, GlpR, H-NS, IHF, MatA, ModE, NarL, NarP, NsrR, PdeL, SutR
Summary: TF Summary ...[more]

REGULATION EXERTED BY FlhDC,ModE,NarL,NarP Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FlhDC activator ModE activator NarL repressor NarP repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
ModE-molybdate activator napFp2 ccmH , ccmG , ccmF , ccmE , ccmD , ccmC , ccmB , ccmA , napC , napB , napH , napG , napA , napD , napF 2303696 2303719 -130.5 gtgaatcaatCGCTATATAAATATATTTATAACCatttgaaatg [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
NarP-phosphorylated repressor napFp2 ccmH , ccmG , ccmF , ccmE , ccmD , ccmC , ccmB , ccmA , napC , napB , napH , napG , napA , napD , napF 2303606 2303621 -37.0 ggttttacccCGATCGGGGTATGCATctttgacaca [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
NarP-phosphorylated repressor napFp2 ccmH , ccmG , ccmF , ccmE , ccmD , ccmC , ccmB , ccmA , napC , napB , napH , napG , napA , napD , napF 2303615 2303630 -46.0 cctgctacagGTTTTACCCCGATCGGggtatgcatc [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
FlhDC activator napFp2 ccmH , ccmG , ccmF , ccmE , ccmD , ccmC , ccmB , ccmA , napC , napB , napH , napG , napA , napD , napF

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Stewart V., et al., 2003



Reference(s)    

 [1] Stewart V., Bledsoe PJ., Williams SB., 2003, Dual overlapping promoters control napF (periplasmic nitrate reductase) operon expression in Escherichia coli K-12., J Bacteriol 185(19):5862-70

 [2] Pruss BM., Liu X., Hendrickson W., Matsumura P., 2001, FlhD/FlhC-regulated promoters analyzed by gene array and lacZ gene fusions., FEMS Microbiol Lett 197(1):91-7

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