RegulonDB RegulonDB 11.1: Regulon Form
   
   


FNR,NfeR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
FNR Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional dual regulator FNR, NirA, NirR, OssA, OxrA
Gene name(s): fnr
Functional conformation(s): FNR , FNR-[4Fe-4S]2+ reduced , FNR-[2Fe-2S]2+ oxidized
Coregulator(s): AcrR, AdiY, ArcA, ArgP, ArgR, BtsR, CRP, CadC, CaiF, Cbl, CdaR, Cra, CueR, CusR, CysB, DcuR, DksA, DksA-ppGpp, DnaA, DpiA, EvgA, ExuR, FNR, FhlA, Fis, FlhDC, Fur, GadE, GadE-RcsB, GadW, GadX, GcvA, GlpR, H-NS, HdfR, HprR, HyfR, HypT, IHF, LeuO, Lrp, MalT, MarA, MetR, MlrA, ModE, Nac, NagC, NarL, NarP, NfeR, NikR, NorR, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PhoB, PhoP, PurR, PuuR, RcsB, Rob, RstA, RutR, SlyA, SoxR, SoxS, TdcA, TdcR, TorR, YeiL, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
NfeR      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional repressor NfeR, YqjI
Gene name(s): nfeR
Functional conformation(s): NfeR , NfeR-Fe2+ , NfeR-Ni2+
Coregulator(s): FNR, Fur, NfeR
Summary: TF Summary ...[more]

REGULATION EXERTED BY FNR,NfeR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FNR activator NfeR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
NfeR repressor nfeRp nfeR 3216731 3216762 -7.0 aagaacgctcATATCAGATATAAATTAGATATATCTAATTAAgcaaaaggag [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
FNR activator nfeRp nfeR

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Wang S., et al., 2014
[2] Wang S., et al., 2011



Reference(s)    

 [1] Wang S., Blahut M., Wu Y., Philipkosky KE., Outten FW., 2014, Communication between binding sites is required for YqjI regulation of target promoters within the yqjH-yqjI intergenic region., J Bacteriol 196(17):3199-207

 [2] Wang S., Wu Y., Outten FW., 2011, Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli., J Bacteriol 193(2):563-74

 [3] Constantinidou C., Hobman JL., Griffiths L., Patel MD., Penn CW., Cole JA., Overton TW., 2006, A reassessment of the FNR regulon and transcriptomic analysis of the effects of nitrate, nitrite, NarXL, and NarQP as Escherichia coli K12 adapts from aerobic to anaerobic growth., J Biol Chem 281(8):4802-15

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