RegulonDB

TRANSCRIPTION FACTOR:

Name:

NorR	Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional dual regulator NorR, YgaA

Gene name(s):

norR

Functional conformation(s):

NorR

Coregulator(s):

FNR, IHF, NarL, NarP, NorR, NsrR

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

NsrR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional regulator NsrR, YjeB

Gene name(s):

nsrR

Functional conformation(s):

NsrR , NsrR-[2Fe-2S]reduced , NsrR-[2Fe-2S]²⁺ oxidized , NsrR-nitric oxide

Coregulator(s):

ArcA, CRP, CpxR, CsgD, CytR, DksA, DksA-ppGpp, DsdC, FNR, FeaR, FhlA, Fis, FlhDC, Fur, GadE, H-NS, IHF, IscR, Lrp, MatA, MetR, ModE, Nac, NarL, NarP, NorR, NsrR, OxyR, PdhR, PhoB, QseB, SutR, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY NorR,NsrR

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
NorR repressor NsrR repressor
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
NorR	repressor	norRp	norR	2832346	2832358	-45.0	attaatgagtAGTCAAAATGACTatcaatcaaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [2] [3]
NorR	repressor	norRp	norR	2832322	2832334	-21.0	tcaatcaaatGGTCGATATGACAatatctatag	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [3]
NorR	repressor	norRp	norR	2832301	2832313	1.0	caatatctatAGTCAAATTGACAgtgaggcaaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [3]
NsrR	repressor	norRp	norR	2832282	2832293	21.0	acagtgaggcAAAGATGAGTTTttccgttgat	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[4]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Justino MC., et al., 2005 [2] Tucker NP., et al., 2004 [3] Tucker NP., et al., 2006 [4] Partridge JD., et al., 2009

Reference(s)
[1] Justino MC., Goncalves VM., Saraiva LM., 2005, Binding of NorR to three DNA sites is essential for promoter activation of the flavorubredoxin gene, the nitric oxide reductase of Escherichia coli., Biochem Biophys Res Commun 328(2):540-4
[2] Tucker NP., D'Autr?aux B., Studholme DJ., Spiro S., Dixon R., 2004, DNA binding activity of the Escherichia coli nitric oxide sensor NorR suggests a conserved target sequence in diverse proteobacteria., J Bacteriol 186(19):6656-60
[3] Tucker NP., D'autreaux B., Spiro S., Dixon R., 2006, Mechanism of transcriptional regulation by the Escherichia coli nitric oxide sensor NorR., Biochem Soc Trans 34(Pt 1):191-4
[4] Partridge JD., Bodenmiller DM., Humphrys MS., Spiro S., 2009, NsrR targets in the Escherichia coli genome: new insights into DNA sequence requirements for binding and a role for NsrR in the regulation of motility., Mol Microbiol 73(4):680-94