RegulonDB

TRANSCRIPTION FACTOR:

Name:

PhoB	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional dual regulator PhoB, PhoB response regulator, PhoT

Gene name(s):

phoB

Functional conformation(s):

PhoB , PhoB-phosphorylated

Coregulator(s):

AlpA, ArgP, AscG, CRP, CpxR, CusR, EnvY, FNR, Fur, GadE, GadE-RcsB, GadW, GadX, H-NS, HprR, IHF, Nac, NsrR, OmpR, PhoB, PrpR, QseB, RcdA, RstA, RutR

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

NsrR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional regulator NsrR, YjeB

Gene name(s):

nsrR

Functional conformation(s):

NsrR , NsrR-[2Fe-2S]reduced , NsrR-[2Fe-2S]²⁺ oxidized , NsrR-nitric oxide

Coregulator(s):

ArcA, CRP, CpxR, CsgD, CytR, DksA, DksA-ppGpp, DsdC, FNR, FeaR, FhlA, Fis, FlhDC, Fur, GadE, H-NS, IHF, IscR, Lrp, MatA, MetR, ModE, Nac, NarL, NarP, NorR, NsrR, OxyR, PdhR, PhoB, QseB, SutR, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY NsrR,PhoB

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
NsrR repressor PhoB activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
PhoB-phosphorylated	activator	yibDp1	waaH	3790249	3790276	-113.0	ctgaggataaTCTGTTAAATATGTAAAATCCTGTCAGTgtaataaaga	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
PhoB-phosphorylated	activator	yibDp1	waaH	3790199	3790219	-59.5	tgtgctgatcTCTTATATAGCTGCTCTCATTatctctctac	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
NsrR	repressor	yibDp1	waaH	3790259	3790270	-115.0	ataatctgttAAATATGTAAAAtcctgtcagt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[2]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Baek JH., et al., 2006 [2] Partridge JD., et al., 2009

Reference(s)
[1] Baek JH., Lee SY., 2006, Novel gene members in the Pho regulon of Escherichia coli., FEMS Microbiol Lett 264(1):104-9
[2] Partridge JD., Bodenmiller DM., Humphrys MS., Spiro S., 2009, NsrR targets in the Escherichia coli genome: new insights into DNA sequence requirements for binding and a role for NsrR in the regulation of motility., Mol Microbiol 73(4):680-94