RegulonDB

TRANSCRIPTION FACTOR:

Name:

CreB	Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

CreB response regulator, DNA-binding transcriptional regulator CreB, YjjE

Gene name(s):

creB

Functional conformation(s):

CreB , CreB-phosphorylated

Coregulator(s):

CRP, CreB, Fis, H-NS, MalT, StpA

Summary:

TF Summary ...[more]

REGULATION EXERTED BY CreB

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
CreB activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
CreB-phosphorylated	activator	creDp	creD	4638099	4638117	-52.5	cctcgcttcgACTTCACCGTCACTTCACAtagcttcaaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [2]
CreB-phosphorylated	activator	talAp	talA	2578388	2578406	-211.5	ttggttgttcCTTTCACGTAACGTTCACAaataaagtgt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Avison MB., et al., 2001 [2] Cariss SJ., et al., 2008

Reference(s)
[1] Avison MB., Horton RE., Walsh TR., Bennett PM., 2001, Escherichia coli CreBC is a global regulator of gene expression that responds to growth in minimal media., J Biol Chem 276(29):26955-61
[2] Cariss SJ., Tayler AE., Avison MB., 2008, Defining the growth conditions and promoter-proximal DNA sequences required for activation of gene expression by CreBC in Escherichia coli., J Bacteriol 190(11):3930-9