RegulonDB RegulonDB 11.1: Regulon Form
   
   


Fur,NfeR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
NfeR      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional repressor NfeR, YqjI
Gene name(s): nfeR
Functional conformation(s): NfeR , NfeR-Fe2+ , NfeR-Ni2+
Coregulator(s): FNR, Fur, NfeR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
Fur Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): DNA-binding transcriptional dual regulator Fur
Gene name(s): fur
Functional conformation(s): Fur-Fe2+ , Fur , Fur-Mn2+
Coregulator(s): AcrR, AdiY, ArcA, ArgP, ArgR, CRP, CdaR, CpxR, Cra, CusR, EnvY, FNR, Fis, FliZ, Fur, GadE, GadX, H-NS, HdfR, HprR, HypT, IHF, IscR, LrhA, Lrp, MarA, MatA, MetR, MntR, ModE, MqsA, Nac, NagC, NarL, NfeR, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PhoB, PurR, QseB, RcnR, RcsAB, Rob, RstA, RutR, SlyA, SoxR, SoxS, YjjQ, Zur, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY Fur,NfeR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
Fur repressor NfeR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
NfeR repressor yqjHp nfeF 3216512 3216531 18.0 ttgcgagtttTATTTAGATATATCTGATTAccatcacgaa [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
Fur-Fe2+ repressor yqjHp nfeF 3216544 3216562 -15.0 tgcatttatcATGATTAACAATCATTATCatttgcgagt [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
[2]
Fur-Fe2+ repressor yqjHp nfeF 3216538 3216556 -9.0 tatcatgattAACAATCATTATCATTTGCgagttttatt [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
[2]
Fur-Fe2+ repressor yqjHp nfeF 3216548 3216566 -19.0 cgcttgcattTATCATGATTAACAATCATtatcatttgc [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
[2]

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Wang S., et al., 2014
[2] Wang S., et al., 2011
[3] McHugh JP., et al., 2003



Reference(s)    

 [1] Wang S., Blahut M., Wu Y., Philipkosky KE., Outten FW., 2014, Communication between binding sites is required for YqjI regulation of target promoters within the yqjH-yqjI intergenic region., J Bacteriol 196(17):3199-207

 [2] Wang S., Wu Y., Outten FW., 2011, Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli., J Bacteriol 193(2):563-74

 [3] McHugh JP., Rodriguez-Quinones F., Abdul-Tehrani H., Svistunenko DA., Poole RK., Cooper CE., Andrews SC., 2003, Global iron-dependent gene regulation in Escherichia coli. A new mechanism for iron homeostasis., J Biol Chem 278(32):29478-86

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