RegulonDB

TRANSCRIPTION FACTOR:

Name:

QseB	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional activator QseB, QseB response regulator, YgiX

Gene name(s):

qseB

Functional conformation(s):

QseB-Phosphorylated , QseB

Coregulator(s):

AcrR, BasR, CRP, FliZ, Fur, H-NS, HdfR, IHF, LrhA, Lrp, MatA, Nac, NsrR, OmpR, PhoB, QseB, RcsAB, YjjQ

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

BasR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

BasR response regulator, DNA-binding transcriptional dual regulator BasR, PmrA

Gene name(s):

basR

Functional conformation(s):

BasR-phosphorylated , BasR

Coregulator(s):

BasR, BolA, BtsR, CRP, CpxR, Cra, CsgD, DksA, DksA-ppGpp, Fis, FliZ, H-NS, IHF, MarA, MlrA, MqsA, NagC, NanR, OmpR, PdhR, PhoP, PutA, QseB, RcdA, RcsAB, RstA, SoxR, SoxS, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY BasR,QseB

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
BasR activator QseB activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
QseB-Phosphorylated	activator	qseBp2	qseB , qseC	3169281	3169293	-462.0	ggagcggtaaCAATTACGGATTTactttgcgga	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
QseB-Phosphorylated	activator	qseBp2	qseB , qseC	3169748	3169760	6.0	ttaagggaaaAAAATAAAATTTAgtgctgtaca	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
BasR-phosphorylated	activator	qseBp2	qseB , qseC	3169726	3169745	-13.5	caagatagtcCTTAACAACTTCTTAAGGGAaaaaaataaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[2]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Clarke MB., et al., 2005 [2] Guckes KR., et al., 2013

Reference(s)
[1] Clarke MB., Sperandio V., 2005, Transcriptional autoregulation by quorum sensing Escherichia coli regulators B and C (QseBC) in enterohaemorrhagic E. coli (EHEC)., Mol Microbiol 58(2):441-55
[2] Guckes KR., Kostakioti M., Breland EJ., Gu AP., Shaffer CL., Martinez CR., Hultgren SJ., Hadjifrangiskou M., 2013, Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor., Proc Natl Acad Sci U S A 110(41):16592-7