RegulonDB

TRANSCRIPTION FACTOR:

Name:

CRP	Weight Matrix Tractordb tool

Connectivity class

Global Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

Cap, Csm, DNA-binding transcriptional dual regulator CRP, GurB

Gene name(s):

crp

Functional conformation(s):

CRP , CRP-cyclic-AMP

Coregulator(s):

AaeR, AcrR, AdiY, AgaR, AraC, ArcA, ArgP, ArgR, AscG, BasR, BolA, BtsR, CRP, CRP-Sxy, CaiF, ChbR, ComR, CpxR, Cra, CreB, CsgD, CspA, CsqR, CusR, CytR, DcuR, DeoR, DgoR, DksA-ppGpp, DnaA, DpiA, DsdC, EbgR, EnvY, EvgA, ExuR, FNR, FadR, FeaR, FhlA, Fis, FlhDC, FliZ, FrlR, FucR, Fur, GadE, GadE-RcsB, GadW, GadX, GalR, GalS, GatR, GcvA, GlaR, GlcC, GlpR, GlrR, GntR, GutM, H-NS, HU, HdfR, HipB, HprR, HyfR, HypT, IHF, IclR, IdnR, LacI, LeuO, LexA, LrhA, Lrp, LsrR, MalI, MalT, MarA, MarR, MatA, McbR, MelR, MetJ, MhpR, Mlc, MlrA, ModE, MprA, MqsA, MurR, Nac, NadR, NagC, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PhoB, PhoP, PlaR, PrpR, PurR, PuuR, QseB, RbsR, RcdA, RcsAB, RcsB, RcsB-BglJ, RhaR, RhaS, Rob, RspR, RstA, SdiA, SlyA, SoxR, SoxS, SrlR, StpA, TdcA, TdcR, TorR, TreR, UhpA, UidR, UlaR, UvrY, UxuR, XylR, YdeO, YjjQ, ZraR, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

RcsB	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional activator RcsB, RcsB response regulator

Gene name(s):

rcsB

Functional conformation(s):

RcsB-phosphorylated , RcsB , RcsB-acetylated

Coregulator(s):

AdiY, ArcA, CRP, CadC, CpxR, EvgA, FNR, Fis, FliZ, GadE, GadE-RcsB, GadW, GadX, GlrR, H-NS, LeuO, LexA, Lrp, MarA, NagC, NarL, NarP, NhaR, NtrC, OmpR, PhoB, PhoP, RcsB, RcsB-BglJ, Rob, SdiA, StpA, TorR, UvrY, YdeO, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

GlrR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional activator GlrR, GlrR response regulator, QseF, YfhA

Gene name(s):

glrR

Functional conformation(s):

GlrR , GlrR-phosphorylated

Coregulator(s):

CRP, GlrR, IHF, NtrC, RcsB

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

NtrC	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional dual regulator NtrC, GlnG, GlnT, NtrC response regulator

Gene name(s):

glnG

Functional conformation(s):

NtrC-phosphorylated

Coregulator(s):

ArcA, ArgR, CRP, CysB, FNR, Fis, Fur, GadX, GlrR, IHF, Nac, NtrC, PhoP, RcsB, RutR, ppGpp

REGULATION EXERTED BY CRP,GlrR,NtrC,RcsB

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
CRP activator GlrR activator NtrC activator RcsB activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
CRP-cyclic-AMP	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710354	2710371	-23.0	tagcatcatgTTGTGCGGATAAACACCTgctattttaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
RcsB-phosphorylated	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710385	2710398	-52.5	aatttactaaACATGGTTTGGTCAgcatagcatc		[1]
GlrR-phosphorylated	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710420	2710440	-90.5	cgtcacatgaATGTTCAGGGAGAGTATTCATtttctttgtt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
GlrR-phosphorylated	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710396	2710413	-65.5	tcattttcttTGTTTAATTTACTAAACAtggtttggtc	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
GlrR-phosphorylated	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710357	2710374	-26.5	gcatagcatcATGTTGTGCGGATAAACAcctgctattt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
NtrC-phosphorylated	activator	rpoEp2b	rseC , rseB , rseA , rpoE , rseD	2710364	2710382	-33.5	tttggtcagcATAGCATCATGTTGTGCGGataaacacct		[1]
CRP-cyclic-AMP	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710354	2710371	-23.0	tagcatcatgTTGTGCGGATAAACACCTgctattttaa	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
GlrR-phosphorylated	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710357	2710374	-26.5	gcatagcatcATGTTGTGCGGATAAACAcctgctattt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
RcsB-phosphorylated	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710385	2710398	-52.5	aatttactaaACATGGTTTGGTCAgcatagcatc		[1]
NtrC-phosphorylated	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710364	2710382	-33.5	tttggtcagcATAGCATCATGTTGTGCGGataaacacct		[1]
GlrR-phosphorylated	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710396	2710413	-65.5	tcattttcttTGTTTAATTTACTAAACAtggtttggtc	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
GlrR-phosphorylated	activator	rseDp	rseC , rseB , rseA , rpoE , rseD	2710420	2710440	-90.5	cgtcacatgaATGTTCAGGGAGAGTATTCATtttctttgtt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Klein G., et al., 2016